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Vitamin B-12 1000 mcg Timed-Release

product on market Other (e.g. tea bag) GNC Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Vitamin B12 is supported by strong evidence for maintaining nerve function and supporting red blood cell formation. Calcium is well-documented for its role in bone health and muscle function. However, the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Vitamin B-12 1000 mcg Timed-Release
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
Single Vitamin and Mineral
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1000 mcg (41667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
Calcium
220 mg (17% DV)

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Hydroxypropyl Methylcellulose Hydrogenated Vegetable Oil Calcium Carbonate Silicon Dioxide Magnesium Stearate Carnauba wax Vegetable Acetoglycerides Polyethylene Glycol Calcium Silicate Polysorbate 80 Rice Bran Powder
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one caplet daily.

Warnings & Precautions

Keep out of reach of children.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

Formulation Notes

Essential for carbohydrate metabolism & energy production Required for red blood cell formation

Potency verified by GNC procedure #5037. Conforms to USP <2091> for weight.

No sugar, no artificial colors, no artificial flavors, no preservatives, sodium free, no wheat, gluten free, no dairy. GF Gluten free

Ko Kosher Service

Additional Information

Store in a cool, dry place.

90-day supply

Ko Kosher Service

Metadata

Product Details

UPC / SKU0 48107 17709 6
DSLD Entry Date2020-06-24
Product TypeSingle Vitamin and Mineral
FormOther (e.g. tea bag)
BrandGNC
DSLD ID227906
Data Updated2026-04-11
Research

Research Evidence

237
Research Sources
53
Avg Quality
83
Meta Analysis
74
Systematic Review
45
Rct
29
Clinical Trial
2
Guideline
2
Regulatory Source
1
Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021 PubMed DOI
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024 PubMed DOI
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020 PubMed DOI
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024 PubMed DOI
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024 PubMed DOI
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023 PubMed DOI
View all evidence for Vitamin B12 →
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Vitamin B12 research Best Vitamin B12 All Vitamin B12 products More from GNC View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.