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Acetyl L-Carnitine 500 mg

product on market Capsule GNC Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Acetyl-L-Carnitine hydrochloride is researched for its role in supporting mitochondrial function and cognitive health. There is moderate evidence suggesting it may assist with mental focus and energy metabolism. The ingredient profile maintains a high safety rating for general use.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Acetyl L-Carnitine 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)

Other Ingredients

Gelatin Microcrystalline Cellulose Hydroxypropylcellulose Talc Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take one or two capsules daily with water.

Warnings & Precautions

Keep out of reach of children.

Formulation Notes

Supports positive mood balance

Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

No Sugar, no artificial colors, no artificial flavors, no wheat, gluten free, no corn, no soy, no dairy. GF Gluten Free

Additional Information

60 servings

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 48107 21114 1
DSLD Entry Date2020-06-24
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandGNC
DSLD ID227837
Data Updated2026-04-11
Research

Research Evidence

80
Research Sources
49
Avg Quality
43
Rct
14
Clinical Trial
11
Systematic Review
9
Meta Analysis
2
Regulatory Source
A Propionyl-L-carnitine for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Carnitine supplements for people with chronic kidney disease requiring dialysis
Systematic Review The Cochrane database of systematic reviews 2022 PubMed DOI
A Acetyl-L-carnitine for patients with hepatic encephalopathy
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
B Carnitine for fatigue in multiple sclerosis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B L-carnitine for cognitive enhancement in people without cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Carnitine for fatigue in multiple sclerosis
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Systematic Review and Meta-analysis on Effect of Carnitine, Coenzyme Q10 and Selenium on Pregnancy and Semen Parameters in Couples With Idiopathic Male Infertility
Meta Analysis Urology 2022 PubMed DOI
B Effects of Carnitine and Coenzyme Q10 on Sperm Quality and Pregnancy Rates in Men with Unexplained Infertility: A Systematic Review and Network Meta-Analysis
Systematic Review Reproductive sciences (Thousand Oaks, Calif.) 2025 PubMed DOI
B Efficacy and Effectiveness of Carnitine Supplementation for Cancer-Related Fatigue: A Systematic Literature Review and Meta-Analysis
Meta Analysis Nutrients 2017 PubMed DOI
View all evidence for Carnitine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.