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Calcimate Plus with Magnesium & Vitamin D-3

product on market Other (e.g. tea bag) GNC Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium, magnesium, and vitamin D are supported by strong evidence for maintaining bone density and skeletal health. These nutrients work synergistically to regulate mineral absorption and support neuromuscular function. Research indicates these ingredients are generally safe for supplementation when taken as directed.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calcimate Plus with Magnesium & Vitamin D-3
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
125
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mcg (250% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
Calcium
800 mg (62% DV)
100 mg (24% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)

Other Ingredients

Microcrystalline Cellulose Povidone Hydroxypropyl Methylcellulose Magnesium Stearate Titanium Dioxide Silicon Dioxide Croscarmellose Sodium Sodium Starch Glycolate Vegetable Acetoglycerides Polyethylene Glycol Carnauba wax Polysorbate 80
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take two caplets at breakfast and two caplets at dinner for a total of four caplets daily.

Warnings & Precautions

Keep out of reach of children.

Formulation Notes

Premium GNC formula

Essential for building strong bones

Features calcium citrate malate, one of the most absorbable forms of calcium

With 100 mg of magnesium & 50 mcg (2000 IU) of vitamin D-3

Calcium is essential for building healthy bones. Calcimate Plus features Calcium Citrate Malate (CCM), one of the most absorbable and effective forms of calcium.

CCM helps maintain and improve bone density.

Enhanced with magnesium and vitamin D-3, required during the growth and development of bones to help achieve and maintain peak bone density.

All mineral amounts shown are elemental. Potencies verified by GNC procedure #4000. Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

No artificial flavors, sodium free, no wheat, gluten free, no dairy. GF Gluten free

Additional Information

Store in a cool, dry place.

800 mg Per 4 caplets 125-Day supply

Metadata

Product Details

UPC / SKU0 48107 17778 2
DSLD Entry Date2020-06-24
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandGNC
DSLD ID223579
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.