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5-HTP with Vitamin B6 100 mg

product on market Capsule The Vitamin Shoppe Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

5-HTP serves as a precursor to serotonin, while Vitamin B6 acts as a cofactor in its synthesis. Research provides moderate evidence for their role in supporting mood and sleep regulation. Calcium and phosphorus provide basic mineral support, though evidence for their synergy in this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP with Vitamin B6 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mg (1176% DV)
15.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Calcium
70 mg (5% DV)
54 mg (4% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Microcrystalline Cellulose Gelatin Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one (1) capsule daily, preferably in between meals.

Warnings & Precautions

Warning: Do not use this product if you are pregnant or nursing or taking any antidepressant medications such as selective serotonin reuptake inhibitors (SSRI’s), tricyclic antidepressants or monamine oxidase inhibitors (MAOI). Consult your physician prior to use if you have any medical condition or are taking any medications.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Formulation Notes

Neurotransmitter production Mood support

Gluten-free Dairy-free Soy-free Nut-free

Additional Information

Specialty

Quality Promise Tested & Trusted

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU7 66536 02284 7
DSLD Entry Date2020-05-22
Product TypeOther Combinations
FormCapsule
BrandThe Vitamin Shoppe
DSLD ID221605
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.