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5-HTP 100 mg

product on market Capsule Nested Naturals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP is a precursor to serotonin and is used in research to support mood and sleep regulation. There is moderate evidence suggesting its efficacy for managing depressive symptoms. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
120
Servings
Amino acid/Protein
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Rice Flour Plant Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take 1 vegan capsule daily with water as needed.

Warnings & Precautions

Warning: Use only as directed. Consult your healthcare professional before use if you are pregnant or nursing, have a serious medical condition, or use prescription medications.

Do not use if safety seal is broken.

Formulation Notes

Third party tested Every batch is certified to ensure you get all the good stuff.

Balance the levels of serotonin in your brain to promote a positive mood, relaxation, healthy sleep habits and normal eating patterns. Balanced serotonin levels may help to promote positive moods and offer support during occasional times of stress. Healthy serotonin levels may ease you into a calm relaxed state, helping you drift off to sleep.

Balanced serotonin levels support a healthy state of well-being Positivity Balance Relaxation

Proudly vegan, third-party tested, and manufactured in a NSF certified cGMP facility in the USA using worldwide ingredients.

Proudly vegan, third-party tested, and manufactured in a NSF certified cGMP facility in the USA using worldwide ingredients.

Allergies? We have you covered. Does not contain wheat, gluten, GMO, soy, dairy, egg, fish, nuts, corn, yeast, shellfish or tree nuts.

Additional Information

Our mission: You To better your health & wellness with clean ingredients backed by evidence-based science.

Radically transparent You deserve to know everything that goes into your body. That's why we include every single ingredient on our label. Guaranteed for life We're confident you'll love us, but if you don't... call or email us for a full refund. This bottle makes a difference Each supplement you purchase from us helps improve the nutrition of women and children. Vitamin angels Proud supporter #Getnested

Certified GMP Facility Third Party Tested

Store in a cool, dry place. Avoid excessive heat.

Vegan

Made with love

Metadata

Product Details

UPC / SKU8 52446 00709 5
DSLD Entry Date2020-05-22
Product TypeAmino acid/Protein
FormCapsule
DSLD ID221297
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.