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Bone Matrix

product on market Capsule ProEnzol Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 17% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium, magnesium, and manganese are supported by strong evidence for maintaining bone mineral density and skeletal structure. The herbal and enzyme blends have limited research regarding their specific impact on bone health. Overall, these ingredients are generally recognized as safe for supplementation.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Bone Matrix
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Vegetarian Capsule(s)
Serving Size
45
Servings
Other Combinations
Product Type
17%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
114 mg (9% DV)
76 mg (18% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
2 mg (87% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
Synergistic Herbal Blend
110 mg
Therapeutic Enzyme Blend
74 mg
500 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Plant Fiber Water
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take two (2) capsules three times daily at the beginning of each meal, or as directed by your healthcare professional.

Warnings & Precautions

Caution: If you are pregnant, nursing, have a serious medical condition, or take any medications, consult your healthcare professional before use.

Use only if tamper-evident seal is unbroken.

Keep out of reach of children.

Allergen warning: Contains soy

Formulation Notes

ProEnzol Bone Matrix provides a supportive blend of bioavailable minerals plus synergistic botanical extracts and absorption-enhancing enzymes to promote the normal formation and maintenance of strong, health bone tissue.

Supports healthy bone mineral density

Contains no: sugar, wheat, yeast, gluten, peanuts, tree nuts, eggs, dairy, animal products, artificial colors, flavors and sweeteners or genetically modified organisms (GMOs).

Additional Information

Store tightly closed in a cool, dry place.

Exclusively for professionals

Metadata

Product Details

UPC / SKU7 07636 12231 0
DSLD Entry Date2020-05-22
Product TypeOther Combinations
FormCapsule
DSLD ID221205
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.