🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 40% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size
45 Servings
Botanical Product Type
40% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 250.0mg (60 products) 📚 7 studies (Tier A: 0, B: 1)
This product: 250mg
Skullcap extract
150 mg
California Poppy extract
125 mg
📊 Market median: 333.0mg (166 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 125mg
Linden extract
100 mg

Other Ingredients

Microcrystalline Cellulose Vegetarian Capsule Magnesium Stearate Silica

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (90% of products) No Claim (1% of products) Nutrient (1% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Usage: 2 capsules per day before bedtime or as directed by a health professional.

⚠️ Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

🧪 Formulation Notes

Three Brains is a line of supplements designed to support the critical relationship between our head, heart, and gut. Together, these three "brains" influence our cognition and support a healthy mind.

The Best Sleep combines five non-habit-forming natural ingredients that have been traditionally used by herbalists as mild sleep aids, especially in cases of restlessness or occasional sleeplessness due to everyday mental stress. The ingredients in this unique formula also have an analgesic effect that further promotes relaxed and restful sleep.

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Suitable for vegetarians/vegans.

Supports relaxation & promotes restful sleep

Additional Information

isura Non-GMO - Mass Spec Documentation Lab tested

For freshness, store in a cool, dry place.

Recyclable container and label. Product of Canada

Purity & Potency Guaranteed

Product Details

UPC / SKU 0 68958 03058 6
DSLD Entry Date 2020-05-22
Product Type Botanical
Form Capsule
DSLD ID 220758
Data Updated 2026-04-11

Research Evidence

7 Research Sources
47 Avg Quality Score
6 Rct
1 Meta Analysis
B Passiflora for anxiety disorder
Meta Analysis The Cochrane database of systematic reviews 2007
C Effects of Passiflora incarnata Linnaeus on polysomnographic sleep parameters in subjects with insomnia disorder: a double-blind randomized placebo-controlled study
Rct International clinical psychopharmacology 2020
C Effects of Passiflora incarnata and Valeriana officinalis in the control of anxiety due to tooth extraction: a randomized controlled clinical trial
Rct Oral and maxillofacial surgery 2024
C A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality
Rct Phytotherapy research : PTR 2011
C Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction
Rct Medicina oral, patologia oral y cirugia bucal 2017
C The chronic effects of a combination of herbal extracts (Euphytose®) on psychological mood state and response to a laboratory stressor: A randomised, placebo-controlled, double blind study in healthy humans.
Rct Journal of psychopharmacology (Oxford, England)
D Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam
Rct Journal of clinical pharmacy and therapeutics 2001
View all evidence for Passionflower →

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