🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

1 Tablet(s) Serving Size
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

1000 mcg (41667% DV)
📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 1.0mg

Other Ingredients

Lactose Microcrystalline Cellulose Croscarmellose Sodium Magnesium Stearate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested Usage: Chew and dissolve 1 tablet per day in the mouth before swallowing or as directed by a health professional.

Check with your doctor or health professional on what is the best form and potency for you.

⚠️ Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Contains milk.

🧪 Formulation Notes

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no starch, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.

Suitable for vegetarians.

Quick dissolve

The most metabolically active form

For People with B12 deficiencies it is popular to have injectable vitamin B12; however, research supports that oral administration of an appropriate dosage has been shown to produce as good of results as injectable preparations in treating vitamin B12 deficiency. Methylcobalamin (vitamin B12) is active immediately upon absorption, while other forms (e.g., cyanocobalamin) must be converted to methylcobalamin in a two-step process. Methylcobolamin demonstrates exceptional activity in areas where other forms are simply not active. B12 supplementation is recommended for vegetarians and those with B12 deficiency. It helps form red blood cells, prevent vitamin B12 deficiency and helps maintain good health. In people with low levels of B12, supplementation is very effective in improving energy levels and restoring mental function.

isura This product has passed the most rigorous testing in the world for contaminants and quality. isura.ca

Additional Information

isura Non-GMO - Mass spec Documentation - Lab tested

For freshness, store in a cool, dry place.

Product of Canada Recyclable container and label.

Purity & Potency Guaranteed

R4

Product Details

UPC / SKU 0 68958 01243 8
DSLD Entry Date 2020-05-22
Product Type Vitamin
Form Tablet or Pill
DSLD ID 220095
Data Updated 2026-04-11

Research Evidence

237 Research Sources
53 Avg Quality Score
83 Meta Analysis
74 Systematic Review
45 Rct
29 Clinical Trial
2 Guideline
2 Regulatory Source
1 Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023
View all evidence for Vitamin B12 →

Compare Similar Products

View all Vitamin B12 products →