CoQ-10 400 mg by The Vitamin Shoppe — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Softgel(s) Serving Size

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Coenzyme Q-10

400 mg

📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)

This product: 400mg UL 1200mg

Other Ingredients

Soybean Oil Gelatin Glycerin purified Water Annatto extract Soy Lecithin yellow Beeswax Titanium Dioxide

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (87% of products) Nutrient (13% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take one (1) softgel daily, preferably with a meal.

⚠️ Warnings & Precautions

Contains: Soy.

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Statin medications may deplete CoQ-10 in the body. Supplementation with Vitamin Shoppe brand CoQ-10 promotes CoQ-10 levels and may help prevent medication-induced depletion.

Keep out of reach of children.

Tamper Evident Do not use if outer seal is broken or missing.

🧪 Formulation Notes

Beneficial for those taking statins

Cardiovascular health Energy production Antioxidant support

Gluten-free Dairy-free Nut-free

Additional Information

Specialty

Quality Promise Tested & Trusted

Store in a cool, dry place.

Product Details

UPC / SKU 7 66536 03369 0

DSLD Entry Date 2020-04-23

Product Type Non-Nutrient/Non-Botanical

Form Softgel Capsule

Brand The Vitamin Shoppe

DSLD ID 218262

Data Updated 2026-04-11

Research Evidence

202 Research Sources

55 Avg Quality Score

86 Meta Analysis

62 Systematic Review

28 Rct

17 Clinical Trial

4 Regulatory Source

2 Other

1 Narrative Review

1 Openfda Safety

A Coenzyme Q10 for heart failure

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI Cochrane

A Cardioprotective interventions for cancer patients receiving anthracyclines

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI

A Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis

Meta Analysis BMJ open 2021

PubMed DOI

A Effects of coenzyme Q10 supplementation on statin-induced myopathy: a meta-analysis of randomized controlled trials

Meta Analysis Irish journal of medical science 2022

PubMed DOI

B Cardioprotective interventions for cancer patients receiving anthracyclines

Meta Analysis The Cochrane database of systematic reviews 2008

PubMed DOI

B Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension

Meta Analysis The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

B Efficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis

Meta Analysis Reproductive sciences (Thousand Oaks, Calif.) 2023

PubMed DOI

B Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials

Meta Analysis International journal of molecular sciences 2020

PubMed DOI

B Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis

Meta Analysis Journal of nutritional science 2025

PubMed DOI

B Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension

Meta Analysis The Cochrane database of systematic reviews 2009

PubMed DOI Cochrane

View all evidence for Coq10 →