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CoQ-10 400 mg

product on market Softgel Capsule The Vitamin Shoppe Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Coenzyme Q-10 is researched for its role in cellular energy production and antioxidant support. There is moderate evidence suggesting it may support cardiovascular health and mitochondrial function. This ingredient is generally well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for CoQ-10 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)

Other Ingredients

Soybean Oil Gelatin Glycerin purified Water Annatto extract Soy Lecithin yellow Beeswax Titanium Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one (1) softgel daily, preferably with a meal.

Warnings & Precautions

Contains: Soy.

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Statin medications may deplete CoQ-10 in the body. Supplementation with Vitamin Shoppe brand CoQ-10 promotes CoQ-10 levels and may help prevent medication-induced depletion.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Formulation Notes

Beneficial for those taking statins

Cardiovascular health Energy production Antioxidant support

Gluten-free Dairy-free Nut-free

Additional Information

Specialty

Quality Promise Tested & Trusted

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU7 66536 02390 5
DSLD Entry Date2020-04-23
Product TypeNon-Nutrient/Non-Botanical
FormSoftgel Capsule
DSLD ID217977
Data Updated2026-04-11
Research

Research Evidence

202
Research Sources
55
Avg Quality
86
Meta Analysis
62
Systematic Review
28
Rct
17
Clinical Trial
4
Regulatory Source
2
Other
1
Narrative Review
1
Openfda Safety
A Coenzyme Q10 for heart failure
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Cardioprotective interventions for cancer patients receiving anthracyclines
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis
Meta Analysis BMJ open 2021 PubMed DOI
A Effects of coenzyme Q10 supplementation on statin-induced myopathy: a meta-analysis of randomized controlled trials
Meta Analysis Irish journal of medical science 2022 PubMed DOI
B Cardioprotective interventions for cancer patients receiving anthracyclines
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
B Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
B Efficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis
Meta Analysis Reproductive sciences (Thousand Oaks, Calif.) 2023 PubMed DOI
B Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials
Meta Analysis International journal of molecular sciences 2020 PubMed DOI
B Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis
Meta Analysis Journal of nutritional science 2025 PubMed DOI
B Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Coq10 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.