Glucosamine HCL by Higher Nature — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Tablet(s) Serving Size

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Glucosamine

665 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 665mg

Other Ingredients

Glucosamine HCl Microcrystalline Cellulose Coating Magnesium Stearate

Label Claims — Verification

❓ All Other

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: Take 1 tablet a day, with meals or as your health professional advises. Do not exceed recommended daily intake.

⚠️ Warnings & Precautions

Warning: Not advisable if taking warfarin.

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

Storage: Store in a cool, dry place out of reach of children.

🧪 Formulation Notes

Does not contain: Artificial colours, flavourings or preservatives, dairy products, gluten, lactose, salt, soya, starch, sugar, wheat, yeast.

Suitable for vegetarians and vegans. This product has not been tested on animals.

Vegetarian formula

Glucosamine molecules form microfibres in muscles, ligaments, cartilage and blood vessels.

Additional Information

Ultimate nutrition

Storage: Store in a cool, dry place out of reach of children.

Product Details

UPC / SKU 5 031013 103421

DSLD Entry Date 2020-04-23

Product Type Non-Nutrient/Non-Botanical

Form Tablet or Pill

Brand Higher Nature

DSLD ID 216976

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →