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Methyl B12 - 15 mg

product on market Lozenge AOR Advanced Orthomolecular Research Advanced Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin B12 is essential for nerve function, DNA synthesis, and the formation of red blood cells. There is strong clinical evidence supporting its role in maintaining neurological health and treating specific deficiencies. This formulation provides a highly bioavailable form of the vitamin to support these metabolic processes.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Methyl B12 - 15 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Lozenge(s)
Serving Size
60
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

45000 mcg (1875000% DV)
18750.0× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Xylitol Microcrystalline Cellulose Hydroxypropyl Cellulose Sodium Stearyl Fumarate Rice syrup
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Dissolve 1 lozenge under the tongue first thing in the morning and repeat 1-3 times a day with/without food, or as directed by a qualified health care practitioner.

Warnings & Precautions

Do not use if safety seal is broken

Warning: Consult a your physician if you are pregnant or lactating or if you have a medical condition, or if you’re taking any medication.

Keep out of reach of children.

To report a serious adverse event or obtain product information, call 1-866-215-0450

Formulation Notes

GMP Manufacturing Quality assured Independent testing

Discussion: Methyl B12-15mg is an ultra-high dose formulation of methylcobalamin, which is a supplemental source of Vitamin B12 that supports the maintenance of normal levels of vitamin B12.

This higher-potency formulation is for persons for whom research supports supplementation at higher levels.

Bio-active vitamin B12

Vegan

Non-GMO Gluten free

Absorbable

AOR guarantees that all ingredients have been declared on the label.

Made without wheat, gluten, corn, nuts, peanuts, sesame seeds, sulfites, mustard, soy, dairy, eggs, fish, shellfish or any animal byproduct.

Additional Information

Store tightly sealed in a cool, dry place

Product of Canada

Metadata

Product Details

UPC / SKU6 24917 08045 2
DSLD Entry Date2020-03-24
Product TypeVitamin
FormLozenge
DSLD ID214700
Data Updated2026-04-11
Research

Research Evidence

237
Research Sources
53
Avg Quality
83
Meta Analysis
74
Systematic Review
45
Rct
29
Clinical Trial
2
Guideline
2
Regulatory Source
1
Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021 PubMed DOI
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024 PubMed DOI
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020 PubMed DOI
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024 PubMed DOI
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024 PubMed DOI
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.