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GS-500 Glucosamine Sulfate

product on market Capsule Nature's Way Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 40% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine sulfate is used to support joint health and manage symptoms of osteoarthritis. Research provides moderate evidence for its efficacy in reducing joint pain, though results vary across studies. Other listed ingredients are basic minerals or nutritional values with limited relevance to therapeutic outcomes.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for GS-500 Glucosamine Sulfate
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
40
Servings
Other Combinations
Product Type
40%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
233 mg (10% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Sodium
150 mg (7% DV)
1.5 Gram(s)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)

Other Ingredients

Cellulose plant-derived Capsule Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Take 3 capsules daily.

Warnings & Precautions

Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing.

If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.

Contains shellfish (crab and shrimp).

Formulation Notes

500 mg of stable form glucosamine per capsule

Helps promote healthy joints Helps support healthy joint cartilage

Gluten free. No wheat, corn, soy, dairy products, yeast-derived ingredients, or artificial colors, flavors, or preservatives.

Stable form Helps support healthy joints & cartilage

Contains shellfish (crab and shrimp).

Additional Information

Since 1969

Metadata

Product Details

UPC / SKU7 63948 01782 9
DSLD Entry Date2019-12-22
Product TypeOther Combinations
FormCapsule
DSLD ID212433
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.