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High Potency Magnesium 400 mg

product on market Softgel Capsule Nature Made Safety: 87/100
87/100

This product is generally safe

  • Magnesium: 400mg is 1.1× the Tolerable Upper Intake Level (350mg)
  • 33% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Magnesium is supported by strong evidence for maintaining nerve function and muscle health. This formulation provides a high dose of the mineral to support these physiological processes. Research indicates a favorable safety profile for most adults when taken as directed.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 400mg is 1.1× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for High Potency Magnesium 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Mineral
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Fat
0.5 Gram(s) (1% DV)
400 mg (100% DV)
Exceeds UL by 1.1× (UL: 350 mg) 316 studies (A:8, B:159)

Other Ingredients

Medium Chain Triglycerides Gelatin Glycerin Water Soy Lecithin Colors added yellow Beeswax
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

One softgel daily

Suggested use: Take one softgel daily, with a meal.

Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: Consult a physician before use, if you have kidney disease or if you are taking prescription medications.

Contains: Soy

Formulation Notes

Magnesium is also essential in the formation of bones and teeth and in converting blood sugar into energy

Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free

Contains: Soy

Additional Information

Supports essential nerve, muscle & heart function

Keep bottles tightly closed. Store in a cool, dry place, out of reach of children.

Magnesium liquid softgels are made to Nature Made's guaranteed purity and potency standards. Valid only for U.S. and Puerto Rico residents.

Metadata

Product Details

DSLD Entry Date2019-11-21
Product TypeMineral
FormSoftgel Capsule
BrandNature Made
DSLD ID209393
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.