🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

333 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 333mg

Other Ingredients

Vegetable Capsule Cellulose Magnesium Stearate Silicon Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Recommendation: Take one capsule before a meal, three times daily.

⚠️ Warnings & Precautions

This bottle was sealed for your protection. Do not use if inner seal is missing or damaged.

🧪 Formulation Notes

IN.FORM Metabolic Age Support Berberine is a natural extract of Indian Barberry root. Berberine was selected for the clinically studied IN.FORM program which supports balance of the microbiome.

Additional Information

010030980116

A balanced microbiome can contribute to healthy metabolic function. Supports gut health to combat endotoxins which can interfere with gut performance and glucose metabolism Supports healthy insulin response Supports already healthy cholesterol and triglyceride levels

Learn more about the IN.FORM clinical study program and complete line of products at NaturesSunshine.com/INFORM When used as part of the IN.FORM program, this product: Supports healthy metabolic age Supports a healthy microbiome Supports healthy body composition Is clinically studied New!

Clincally Studied Program

Product of U.S.A.

Nature's Sunshine uses natural source materials that are subject to color variation.

Product Details

UPC / SKU 0 99904 03098 5
DSLD Entry Date 2019-10-23
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 207891
Data Updated 2026-04-11

Research Evidence

98 Research Sources
55 Avg Quality Score
48 Systematic Review
39 Meta Analysis
4 Rct
4 Clinical Trial
1 Other
1 Narrative Review
1 Openfda Safety
B Efficacy and safety of berberine for dyslipidaemias: A systematic review and meta-analysis of randomized clinical trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2018
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Phytomedicine : international journal of phytotherapy and phytopharmacology 2023
B Effect of Berberine on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2019
B Overall and Sex-Specific Effect of Berberine on Glycemic and Insulin-Related Traits: a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis The Journal of nutrition 2023
B The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review
Meta Analysis Journal of translational medicine 2024
B Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver Disease-Clinical and Pre-Clinical Overview and Systematic Review of the Literature
Systematic Review International journal of molecular sciences 2024
B Efficacy and Safety of Berberine Alone or Combined with Statins for the Treatment of Hyperlipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis The American journal of Chinese medicine 2019
B Effects of Berries, Phytochemicals, and Probiotics on Atherosclerosis through Gut Microbiota Modification: A Meta-Analysis of Animal Studies
Meta Analysis International journal of molecular sciences 2023
B Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial
Rct JAMA network open 2025
View all evidence for Berberine →

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