🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

10.5 mcg (618% DV)
📊 Market median: 10.0mg (1576 products) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 0.0105mg UL 100mg
450 mg (107% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 450mg
✅ 2.7× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 30mg UL 40mg

Other Ingredients

Gelatin Rice Flour Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions for Use: Take 3 Signature ZMA capsules daily for men and 2 capsules daily for women. Take 30-60 minutes before bedtime, preferably on an empty stomach.

⚠️ Warnings & Precautions

Warnings: Consult your physician before using this product if you're taking any medications or are under a physician's care for a medical condition. Not for use by those under the age of 18 or by women that are pregnant, trying to get pregnant or nursing.

Not for use by those under the age of 18 or by women that are pregnant, trying to get pregnant or nursing.

🧪 Formulation Notes

Every product is transparent, filler-free, and formulated with effective doses of research-backed ingredients you can trust.

Additional Information

A signature is a promise. A symbol of your identity. Your mark on the world. Bodybuilding.com was founded on a single promise: Trust. It's who we are and it's in our blood. Our Signature line is built on the same promise. Every product is transparent, filler-free, and formulated with effective doses of research-backed ingredients you can trust. We create the highest quality supplements, so you can focus on leaving a mark of your own.

Manufactured in the USA in a GMP registered facility with domestic and international ingredients.

Supports muscle recovery Promotes restorative sleep

Product Details

UPC / SKU 8 53002 00748 1
DSLD Entry Date 2019-10-23
Product Type Other Combinations
Form Capsule
DSLD ID 207699
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
View all evidence for Vitamin B6 →

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