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600+D3

product on market Tablet or Pill 21st Century Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Vitamin D3 and calcium are supported by strong evidence for maintaining bone density and supporting skeletal health. These ingredients work synergistically to regulate calcium absorption and mineralization in the body. Current research indicates a high safety profile for these nutrients when taken as directed.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 600+D3
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Single Vitamin and Mineral
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mcg (100% DV)
1.3× RDA — within safe limits 608 studies (A:16, B:251)
Calcium
600 mg (46% DV)

Other Ingredients

Maltodextrin Croscarmellose Sodium Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a calcium supplement, adults take one (1) tablet with any meal, twice daily or as directed by a healthcare provider. Do not exceed recommended dosage.

Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

Formulation Notes

Calcium is an important mineral for bone health. Vitamin D3 is added to assist with calcium absorption.

No added Yeast or Artificial Flavors. Gluten Free.

Additional Information

Gluten free

Bone Health Support

Compare vs. Caltrate 600+D3

Individual results may vary.

Store at room temperature.

Guaranteed quality Laboratory tested

Metadata

Product Details

UPC / SKU7 40985 27530 6
DSLD Entry Date2019-10-23
Product TypeSingle Vitamin and Mineral
FormTablet or Pill
Brand21st Century
DSLD ID207526
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.