🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
Single Vitamin and Mineral Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

600 IU (150% DV)
✅ Within RDA (1.0× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.015000000000000001mg UL 0.1mg
Calcium
500 mg (50% DV)

Other Ingredients

Croscarmellose Sodium Cellulose Polyvinyl Alcohol Titanium Dioxide Stearic Acid PEG Talc Magnesium Stearate

Label Claims — Verification

Nutrient
All Other
Approved Health
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: As a calcium supplement, take one (1) tablet twice daily with any meal or as directed by your healthcare provider. Do not exceed recommended dosage.

⚠️ Warnings & Precautions

Contains a shellfish ingredient (oyster shell).

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if: pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

500 mg Calcium 600 IU Vitamin D3

Contains a shellfish ingredient (oyster shell).

Calcium is an important mineral for supporting bone health. Calcium also works to support muscle and nerve function. Vitamin D3 is added to assist with Calcium absoprtion and as support for immune function. Adequate Calcium and Vitamin D3 as part of a healthful diet, along with physical activity, may reduce the risk of osteoporosis in later life.

No added Sugar, Yeast, Preservatives or Artificial Flavors.

Additional Information

Compare Active Ingredients to Os-Cal Extra D3

Support for Bone Health Easy to Swallow

Guaranteed quality Laboratory tested

Individual results may vary.

Store at room temperature.

Product Details

UPC / SKU 7 40985 27520 7
DSLD Entry Date 2019-10-23
Product Type Single Vitamin and Mineral
Form Tablet or Pill
Brand 21st Century
DSLD ID 207518
Data Updated 2026-04-11

Research Evidence

849 Research Sources
56 Avg Quality Score
450 Meta Analysis
152 Rct
137 Systematic Review
73 Clinical Trial
11 Regulatory Source
7 Other
7 Guideline
3 Openfda Safety
2 Cochrane Review
2 Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021
View all evidence for Electrolytes →

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