🟢 80/100

This product is generally safe

  • Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)

Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

400 mg (2500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 11.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 400mg UL 35mg
100 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 100mg

Other Ingredients

Gelatin Magnesium Silicate Magnesium Stearate Cellulose Contains Less Than 2% of

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (22% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a vitamin supplement, adults take one (1) capsule daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

⚠️ Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

No added Sugar, Yeast, Preservatives, Artificial Flavors or Colors.

Gluten free

Niacin (vitamin B-3) plays a role in energy metabolism. Niacin from Inositol Hexanicotinate is a good source of vitamin B-3 with a lower flushing effect than that of niacin.

Additional Information

Individual results may vary.

Store at room temperature.

Flush free

Energy & Circulatory Support

Gluten free

Guaranteed quality Laboratory tested

Product Details

UPC / SKU 7 40985 27089 9
DSLD Entry Date 2019-09-24
Product Type Other Combinations
Form Capsule
Brand 21st Century
DSLD ID 206779
Data Updated 2026-04-11

Research Evidence

32 Research Sources
50 Avg Quality Score
19 Rct
7 Meta Analysis
3 Clinical Trial
2 Other
1 Systematic Review
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines
Meta Analysis The Journal of clinical endocrinology and metabolism 2024
B Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes
Meta Analysis The Cochrane database of systematic reviews 2023
B Effectiveness of inositol, metformin and their combination in women with PCOS undergoing assisted reproduction: systematic review and meta-analysis
Meta Analysis Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2022
B Effects of myo-inositol vs. metformin on hormonal and metabolic parameters in women with PCOS: a meta-analysis
Meta Analysis Irish journal of medical science 2023
B Inositol for subfertile women with polycystic ovary syndrome
Meta Analysis The Cochrane database of systematic reviews 2018
B Treatment of lean PCOS teenagers: a follow-up comparison between Myo-Inositol and oral contraceptives
Rct European review for medical and pharmacological sciences 2021
B The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios
Rct European review for medical and pharmacological sciences 2019
C Investigating the effect of combined use of selenium and Myo-inositol supplements on thyroid function and autoimmune characteristics in thyroid disorders: a systematic review and meta-analysis
Meta Analysis Expert review of endocrinology & metabolism 2024
C Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-controlled clinical trial.
Rct International journal of food sciences and nutrition
View all evidence for Inositol →

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