Echinacea Complex 250 mg by 21st Century — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Vegetarian Capsule(s) Serving Size

100 Servings

Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Echinacea Blend

250 mg

📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)

This product: 250mg

Other Ingredients

Oat Fiber Rice Bran Cellulose Magnesium Silicate Magnesium Stearate Silicon Dioxide Contains Less Than 2% of

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (74% of products) Nutrient (3% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a herbal supplement, adults take two (2) capsules daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

⚠️ Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

Echinacea Complex combines benefits of both Echinacea purpurea extract and Echinacea angustifolia and their polyphenols, to support the immune system.

No added Sugar, Salt, Yeast, Preservatives, Artificial Flavors or Colors.

100% Vegetarian.

Gluten free

Additional Information

Individual results may vary.

Store at room temperature.

Per Daily Serving

Immune System Support

Gluten free

Guaranteed quality Laboratory tested

Product Details

UPC / SKU 7 40985 21691 0

DSLD Entry Date 2019-08-23

Product Type Botanical

Form Capsule

Brand 21st Century

DSLD ID 205815

Data Updated 2026-04-11

Research Evidence

38 Research Sources

52 Avg Quality Score

15 Meta Analysis

12 Systematic Review

6 Rct

2 Clinical Trial

1 Regulatory Source

1 Openfda Safety

A Echinacea for preventing and treating the common cold

Meta Analysis The Cochrane database of systematic reviews 2014

PubMed DOI Cochrane

B Efficacy and safety of Echinacea purpurea in treating upper respiratory infections and complications of otitis media in children: Systematic review and meta-analysis

Meta Analysis Clinical nutrition ESPEN 2025

PubMed DOI

B Echinacea for preventing and treating the common cold

Systematic Review The Cochrane database of systematic reviews 2000

PubMed Cochrane

B Echinacea Supplementation Does Not Impact Aerobic Capacity and Erythropoiesis in Athletes: A Meta-Analysis

Meta Analysis Nutrients 2024

PubMed DOI

B Echinacea for preventing and treating the common cold

Meta Analysis The Cochrane database of systematic reviews 2006

PubMed Cochrane

B Therapeutic Potential of a Natural Blend of Aronia melancarpa, Lonicera caerulea, and Echinacea purpurea Extracts in Treating Upper Respiratory Tract Infections: Preliminary Clinical and In Vitro Immunomodulatory Insights

Rct International journal of molecular sciences 2024

PubMed DOI

B Herbal Medicine in Children With Respiratory Tract Infection: Systematic Review and Meta-Analysis

Meta Analysis Academic pediatrics 2018

PubMed DOI

B Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis

Meta Analysis The Lancet. Infectious diseases 2007

PubMed

B Herbal Medicine for Cough: a Systematic Review and Meta-Analysis

Meta Analysis Forschende Komplementarmedizin (2006) 2015

PubMed DOI

B Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and meta-analysis