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Orthobolic

product on market Capsule Blackstone Labs Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains ingredients like UC-II, curcumin, and boswellia, which have moderate to strong evidence for supporting joint health and reducing inflammation. Palmitoylethanolamide and Cissus quadrangularis are also included, though research on their efficacy in humans is more limited. Together, these compounds target joint comfort and structural integrity.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Orthobolic
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Palmitoylethanolamide
200 mg
Cissus quadrangularis
350 mg
Market median: 375.0mg (171 products) 31 studies (A:1, B:14)
150 mg
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
UC-II Standardized Chicken Cartilage
40 mg
BioPerine Black Pepper (fruit) extract
10 mg

Other Ingredients

Magnesium Stearate Silicon Dioxide Gelatin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions As a dietary supplement, take 2 capsules of Orthobolic with water once daily. Do not exceed 1 serving per day.

Warnings & Precautions

Do not exceed 1 serving per day.

Warning Keep out of reach of children. This product should not be taken by individuals under 18 years of age.

Consult a licensed health professional before taking this product. This product is not intended as a sole source of nutrition and should be consumed in conjunction with an appropriate physical training or exercise program.

You should not take this product if you have any current or pre-existing medical conditions, or if you are pregnant or nursing. Do not take this product if you currently taking any prescription or over-the-counter medications.

Do not exceed recommended serving, as it could result in serious adverse health effects.

Additional Information

Helps to increase joint mobility Supports healthy joints and cartilage Improved overall joint comfort Supports joint strength and flexibility

Keep in a cool, dry place away from light.

Visit our website for additional guidance.

All natural joint formula that can improve joint strength, mobility & reduce joint discomfort

Metadata

Product Details

UPC / SKU6 50348 78216 0
DSLD Entry Date2019-07-24
Product TypeOther Combinations
FormCapsule
DSLD ID204987
Data Updated2026-04-11
Research

Research Evidence

33
Research Sources
55
Avg Quality
17
Systematic Review
12
Meta Analysis
3
Rct
1
Clinical Trial
A Oral herbal therapies for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
B Interventions for treating collagenous colitis
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis
Meta Analysis Seminars in arthritis and rheumatism 2018 PubMed DOI
B Evaluating the efficacy and safety of Curcuma longa, Boswellia serrata, and their mixed formulation in treating knee osteoarthritis: A systematic review and network meta-analysis
Systematic Review Complementary therapies in medicine 2026 PubMed DOI
B Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis
Meta Analysis BMC complementary medicine and therapies 2020 PubMed DOI
B Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis
Systematic Review Frontiers in pharmacology 2022 PubMed DOI
B Interventions for treating collagenous colitis
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
B Ayurvedic interventions for osteoarthritis: a systematic review and meta-analysis
Meta Analysis Rheumatology international 2015 PubMed DOI
B Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis
Meta Analysis Phytotherapy research : PTR 2017 PubMed DOI
B Frankincense: systematic review
Systematic Review BMJ (Clinical research ed.) 2008 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.