Glucosamine & MSM by Natrol — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Capsule(s) Serving Size

180 Servings

Other Combinations Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Potassium

87 mg (2% DV)

Glucosamine Sulfate Dipotassium Chloride

670 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 670mg

Methylsulfonylmethane

500 mg

📊 Market median: 1000.0mg (2 products)

This product: 500mg

Other Ingredients

Gelatin Magnesium Stearate Silicon Dioxide

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Directions: Take 2 capsules, three times daily, with a meal.

⚠️ Warnings & Precautions

Warning: Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

Keep out of reach of children.

Contains: Crustacean shellfish (crab and shrimp)

🧪 Formulation Notes

Natrol Glucosamine & MSM: Glucosamine helps maintain cartilage healthy MSM helps maintain the elasticity of joint tissue and supports joint strength

Contains: Crustacean shellfish (crab and shrimp)

No: Milk, egg, fish, tree nuts, peanuts, wheat, soybeans, yeast, artificial colors or flavors, added sugar or preservatives

Additional Information

Clinically tested ingredients

Store in a cool, dry place.

ITEM: 16124.911 F: 3000330 L: 2008975-17222

Joint mobility Promotes joint flexibility, mobility & healthy cartilage Supports joint comfort Value size

Product Details

UPC / SKU 0 47469 16124 8

DSLD Entry Date 2019-08-23

Product Type Other Combinations

Form Capsule

Brand Natrol

DSLD ID 203338

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →