No-Flush Niacin (Inositol Hexanicotinate) 500 mg by Solgar — Ingredients, Evidence & Safety

Product Label

📄 Open Full PDF View on NIH DSLD →

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)

Label Data

1 Vegetable Capsule(s) Serving Size

Other Combinations Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Niacin

400 mg (2500% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 11.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 400mg UL 35mg

Inositol

100 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 100mg

Other Ingredients

Vegetable Cellulose Silica Vegetable Magnesium Stearate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (78% of products) Nutrient (22% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Kosher Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement for adults, take one (1) vegetable capsule one to two times daily, preferably with a meal or as directed by a healthcare practitioner.

⚠️ Warnings & Precautions

Notice: Most people should not experience flushing when using this product. However a few sensitive individuals may experience a temporary skin flushing (hot feeling and skin redness), burning, itching, or rash caused by an increase in blood flow near the skin. Do not take on an empty stomach. Do not take more than the recommended dose unless prescribed by your healthcare practitioner.

Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your healthcare practitioner before use.

Discontinue use and consult your healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

Do not use if outer bottle seal is missing or damaged.

🧪 Formulation Notes

Niacin / Vitamin B3, is a water-soluble vitamin and is part of the B Complex. It is required for the metabolism of carbohydrates and protein into energy. Niacin supports nervous system health. The unique inositol-bound niacin in this formula allows for gentle, no-flush delivery of niacin to the body.

Solgar’s KOF-K certification #K-1250

Gluten, wheat & dairy free

Suitable for vegans

Free of: Gluten, Wheat, Dairy, Soy, Yeast, Sugar, Sodium, Artificial Flavor, Sweetener, Preservatives and Color.

Additional Information

SOLGB71910 02D

Since 1947

Nervous system support Supports energy metabolism

GF Certified Gluten-free K Parve

Store at room temperature.

Product Details

UPC / SKU 0 33984 01910 2

DSLD Entry Date 2019-05-28

Product Type Other Combinations

Form Capsule

Brand Solgar

DSLD ID 201426

Data Updated 2026-04-11

Research Evidence

32 Research Sources

50 Avg Quality Score

19 Rct

7 Meta Analysis

3 Clinical Trial

2 Other

1 Systematic Review

B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis

Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024

PubMed DOI

B Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines

Meta Analysis The Journal of clinical endocrinology and metabolism 2024

PubMed DOI

B Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes

Meta Analysis The Cochrane database of systematic reviews 2023

PubMed DOI Cochrane

B Effectiveness of inositol, metformin and their combination in women with PCOS undergoing assisted reproduction: systematic review and meta-analysis

Meta Analysis Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2022

PubMed DOI

B Effects of myo-inositol vs. metformin on hormonal and metabolic parameters in women with PCOS: a meta-analysis

Meta Analysis Irish journal of medical science 2023

PubMed DOI

B Inositol for subfertile women with polycystic ovary syndrome

Meta Analysis The Cochrane database of systematic reviews 2018

PubMed DOI

B Treatment of lean PCOS teenagers: a follow-up comparison between Myo-Inositol and oral contraceptives

Rct European review for medical and pharmacological sciences 2021

PubMed DOI

B The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios

Rct European review for medical and pharmacological sciences 2019

PubMed DOI

C Investigating the effect of combined use of selenium and Myo-inositol supplements on thyroid function and autoimmune characteristics in thyroid disorders: a systematic review and meta-analysis

Meta Analysis Expert review of endocrinology & metabolism 2024

PubMed DOI

C Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-controlled clinical trial.

Rct International journal of food sciences and nutrition

PubMed DOI

View all evidence for Inositol →