🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
Single Vitamin and Mineral Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

100 mcg (4167% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
Calcium
35 mg (3% DV)

Other Ingredients

Microcrystalline Cellulose Dicalcium Phosphate Stearic Acid Silica Magnesium Stearate Maltodextrin

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Sugar Free

Product Information

📋 Directions for Use

Directions: Adults- take one tablet daily, as a dietary supplement or as directed by your doctor.

⚠️ Warnings & Precautions

Tamper resistant - Do not use if imprinted safety seal under cap is broken or missing.

As with any supplement, if you are pregnant, nursing, taking medication or have a medical condition, consult a doctor before use.

Keep out of reach of children.

🧪 Formulation Notes

Free of sugar, starch, sodium, gluten, preservatives, yeast, animal by-products, soy, artificial colors-flavors.

Additional Information

To preserve quality and freshness, keep bottle tightly closed. Store at room temperature in a dry place.

Rev. 12/16 R-95 Re-order No. 370315

Product Details

UPC / SKU 0 05363 54201 3
DSLD Entry Date 2019-07-24
Product Type Single Vitamin and Mineral
Form Tablet or Pill
Brand Rugby
DSLD ID 201386
Data Updated 2026-04-11

Research Evidence

237 Research Sources
53 Avg Quality Score
83 Meta Analysis
74 Systematic Review
45 Rct
29 Clinical Trial
2 Guideline
2 Regulatory Source
1 Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023
View all evidence for Vitamin B12 →

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