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Niacin Flush Free Inositol Hexanicotinate 500 mg

product on market Other (e.g. tea bag) up&up Safety: 87/100
87/100

This product is generally safe

  • Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Inositol hexanicotinate provides a flush-free form of niacin, which is supported by moderate evidence for supporting lipid metabolism and cardiovascular health. Research indicates that niacin helps manage cholesterol levels, while inositol plays a role in cellular signaling. The overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 400mg is 11.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Niacin Flush Free Inositol Hexanicotinate 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 g (1% DV)
400 mg (2000% DV)
Exceeds UL by 11.4× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Microcrystalline Cellulose Dicalcium Phosphate Hydroxypropyl Cellulose Croscarmellose Sodium Hypromellose Stearic Acid Acacia Silicon Dioxide Magnesium Stearate Ethylcellulose Shellac Wax Triacetin Acetylated Monoglycerides Polyethylene Glycol Oleic Acid
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults, take one (1) caplet once daily with food.

Warnings & Precautions

Discontinue use and consult a doctor if any adverse reactions occur.

NOTICE: Most people should not experience flushing when using this product. However, a few sensitive individuals may experience some flushing. Do not take on an empty stomach.

Keep out of the reach of children.

Caution: Do not use this product is you are pregnant or nursing a baby. Ask a doctor before taking this product if you are taking any medication, planning any medical procedure or have any medical condition including but not limited to: a known sensitivity to niacin, diabetes, heart problems, peptic ulcer disease, gall bladder disease, blood pressure problems, liver or kidney disease, gout or bleeding problems.

Formulation Notes

No artificial colors, artificial flavors, preservatives, wheat, gluten milk or milk derivatives, wheat, gluten, milk or milk derivatives, yeast, lactose, sugar.

GLUTEN FREE

Additional Information

{Caplet} ACTUAL SIZE

Niacin is part of the B vitamin group and is essential for life. Niacin helps maintains the health of the nervous system and supports energy metabolism.

Store in a dry place at room temperature (59(0)-86(0)F).

{Arrow} up&up(R)

094 02 0836 : 8X382 UW F1

EXP11/14 2MN1620

helps support energy metabolism and nervous system health

ID692477

Metadata

Product Details

UPC / SKU0 70030 62482 8
DSLD Entry Date2013-03-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
Brandup&up
DSLD ID20020
Data Updated2026-04-11
Research

Research Evidence

32
Research Sources
50
Avg Quality
19
Rct
7
Meta Analysis
3
Clinical Trial
2
Other
1
Systematic Review
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024 PubMed DOI
B Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS Guidelines
Meta Analysis The Journal of clinical endocrinology and metabolism 2024 PubMed DOI
B Antenatal dietary supplementation with myo-inositol for preventing gestational diabetes
Meta Analysis The Cochrane database of systematic reviews 2023 PubMed DOI
B Effectiveness of inositol, metformin and their combination in women with PCOS undergoing assisted reproduction: systematic review and meta-analysis
Meta Analysis Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2022 PubMed DOI
B Effects of myo-inositol vs. metformin on hormonal and metabolic parameters in women with PCOS: a meta-analysis
Meta Analysis Irish journal of medical science 2023 PubMed DOI
B Inositol for subfertile women with polycystic ovary syndrome
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
B Treatment of lean PCOS teenagers: a follow-up comparison between Myo-Inositol and oral contraceptives
Rct European review for medical and pharmacological sciences 2021 PubMed DOI
B The 40:1 myo-inositol/D-chiro-inositol plasma ratio is able to restore ovulation in PCOS patients: comparison with other ratios
Rct European review for medical and pharmacological sciences 2019 PubMed DOI
C Investigating the effect of combined use of selenium and Myo-inositol supplements on thyroid function and autoimmune characteristics in thyroid disorders: a systematic review and meta-analysis
Meta Analysis Expert review of endocrinology & metabolism 2024 PubMed DOI
C Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-controlled clinical trial.
Rct International journal of food sciences and nutrition PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.