🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

6.7 mg (45% DV)
✅ Within RDA (0.4× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 6.7mg UL 1000mg
Chrysin
500 mg
Polygonum cuspidatum extract
300 mg
📊 Market median: 200.0mg (3 products) 📚 10 studies (Tier A: 1, B: 3)
This product: 100mg

Other Ingredients

Gelatin Cellulose

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (81% of products) Nutrient (56% of products) Qualified Health (2% of products)

Target Groups

Adult Male (18-50 Years)

Product Information

📋 Directions for Use

Adult Men: Take two (2) capsules in the morning, with or without food.

⚠️ Warnings & Precautions

Use only as directed.

Consult your healthcare practitioner if you have or suspect a medical condition or if you use any medications as extracts may alter the potency and/or side effects of certain medications.

Discontinue use two weeks prior to surgery or if any serious adverse reaction occurs. Do not use if safety seal is missing.

Keep out of the reach of children.

🧪 Formulation Notes

One of the key super ingredients found in Nugenix Estro-Regulator is Diindolylmethane (DIM), which is an aromatase inhibitor that can help support estrogen balance - a critical factor for anyone wanting hardcore gains.

Featuring: Chrysin & DIM

Precautions: Only for adult males over 18 years.

Additional Information

In vitro evidence demonstrates DIM’s anti-estrogen activity. Through its interaction with estrogen binding sites, it can help inhibit the reaction that converts testosterone into estrogen. Overall, this activity can diminish the impact estrogen has in the body!

Powerful anti-aromastase modulator

Helps to: Support estrogen regulation Reduce aromatization or testosterone Support hormonal balance

Keep product at room temperature and humidity [59-86(0)F (15-30(0)C), 40% RH].

R1

Product Details

UPC / SKU 8 55710 00238 3
DSLD Entry Date 2019-02-25
Product Type Other Combinations
Form Capsule
Brand Nugenix
DSLD ID 199814
Data Updated 2026-04-11

Research Evidence

253 Research Sources
55 Avg Quality Score
128 Meta Analysis
52 Systematic Review
41 Rct
24 Clinical Trial
3 Regulatory Source
1 Narrative Review
1 Other
1 Guideline
1 Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022
View all evidence for Vitamin E →

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