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DAO Histamine Digester with Bioflavonoids

product on market Capsule NutriCology Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Diamine oxidase is used to degrade dietary histamine, while quercetin and rutin act as flavonoids that may stabilize mast cells. Research evidence for these ingredients in managing histamine intolerance is generally limited. The profile maintains a high safety rating with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for DAO Histamine Digester with Bioflavonoids
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Non-Nutrient/Non-Botanical
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Diamine Oxidase
41 mg
50 mg
Market median: 500.0mg (19 products)
50 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose Sucrose Rice Starch Shellac Hydroxypropylcellulose Polyvinylpolypyrrolidone Talc Corn Starch Carboxymethylcellulose Glycerol L-Leucine
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use As a dietary supplement, 1 capsule one or two times daily with histamine-rich foods, or as directed by a healthcare professional.

Warnings & Precautions

Caution: If pregnant or nursing, consult your healthcare practitioner before use.

Keep out of reach of children.

Formulation Notes

DAO Histamine Digester contains diamine oxidase (DAO), an intestinal enzyme that digests histamine. The body produces DAO to digest excess food-derived histamine in the lower intestine. The formula is enhanced with rutin and quercetin.

Additional Information

Store in a cool, dry place, tightly capped.

Rev. 003

Innovative Nutrition

Metadata

Product Details

UPC / SKU7 13947 56880 8
DSLD Entry Date2019-04-25
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
DSLD ID199687
Data Updated2026-04-11
Research

Research Evidence

184
Research Sources
55
Avg Quality
91
Systematic Review
75
Meta Analysis
7
Rct
7
Clinical Trial
2
Cochrane Review
1
Openfda Safety
B Treatment of gouty arthritis with traditional Chinese medicine decoction: Meta-analysis, network pharmacology analysis, and molecular docking
Meta Analysis Medicine 2024 PubMed DOI
B Effects of quercetin supplementation on lipid profile: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2017 PubMed
B Dietary polyphenols and the risk of metabolic syndrome: a systematic review and meta-analysis
Meta Analysis BMC endocrine disorders 2024 PubMed DOI
B Quercetin and endurance exercise capacity: a systematic review and meta-analysis
Meta Analysis Medicine and science in sports and exercise 2011 PubMed DOI
B Dietary flavonoid intake and smoking-related cancer risk: a meta-analysis
Meta Analysis PloS one 2013 PubMed DOI
B Clinical efficacy evaluation and potential mechanism prediction on Guizhi-Shaoyao-Zhimu decoction in the treatment of gouty arthritis based on meta-analysis, network pharmacology analysis, and molecular docking
Meta Analysis Medicine 2023 PubMed DOI
B A Systematic Review: Quercetin-Secondary Metabolite of the Flavonol Class, with Multiple Health Benefits and Low Bioavailability
Systematic Review International journal of molecular sciences 2024 PubMed DOI
B Dietary flavonoid for preventing colorectal neoplasms.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Flavonoids for treating venous leg ulcers.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B The effects of quercetin supplementation on lipid profiles and inflammatory markers among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2020 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.