Vitamin E 400 IU by up&up — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Softgel(s) Serving Size

Vitamin Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin E

400 IU (1333% DV)

📊 17.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 268.0mg UL 1000mg

Other Ingredients

DL-Alpha-Tocopheryl Acetate Gelatin Polysorbate 80 Glycerin

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (98% of products) Structure/Function (81% of products) Nutrient (56% of products) Qualified Health (2% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested use: As a Vitamin E supplement for adults, take one softgel daily with the meal of your choice.

⚠️ Warnings & Precautions

If you are pregnant or nursing a baby, ask a doctor before using this product. If you are taking medication, facing surgery or have bleeding problems, consult your physician before taking this product.

Keep out of reach of children.

🧪 Formulation Notes

No yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, artificial color, artificial flavor, sodium.

GLUTEN FREE

Additional Information

ACTUAL SIZE

water dispersible helps support heart, cardiovascular and immune health* E HEART HEALTH*

EXP 06/16 2HN1776

094 02 1380 : 2K385 UW F1

Shop Target.com

HEART HEALTH* As an antioxidant, Vitamin E helps fight cell-damaging free radicals in the body.* Free radicals can contribute to oxidative stress, which in turn may contribute to the premature aging of cells.* In addition, Vitamin E promotes heart health and immune function, and helps support cardiovascular health.*

Store in a dry place at room temperature (59(0)-86(0)F).

ID482463

Product Details

UPC / SKU 0 70030 62459 0

DSLD Entry Date 2013-03-25

Product Type Vitamin

Form Softgel Capsule

Brand up&up

DSLD ID 19964

Data Updated 2026-04-11

Research Evidence

253 Research Sources

55 Avg Quality Score

128 Meta Analysis

52 Systematic Review

41 Rct

24 Clinical Trial

3 Regulatory Source

1 Narrative Review

1 Other

1 Guideline

1 Openfda Safety

A Vitamin E supplementation in pregnancy

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Systematic Review The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin E for Alzheimer's disease and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2008

PubMed DOI Cochrane

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

A Exercise for intermittent claudication

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis

Meta Analysis Nutritional neuroscience 2021

PubMed DOI

A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis

Meta Analysis European journal of clinical nutrition 2023

PubMed DOI

A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

Rct JAMA 2011

PubMed DOI

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.

Guideline JAMA 2022

PubMed DOI

View all evidence for Vitamin E →