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Magnesium Oxide 400 mg

product on market Capsule The Vitamin Shoppe Safety: 60/100
60/100

Review before taking

  • Magnesium: 400mg is 1.1× the Tolerable Upper Intake Level (350mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Magnesium supports muscle and nerve function, though evidence for magnesium oxide's bioavailability is limited. Due to a safety score of 60, users should be aware of potential gastrointestinal side effects. Consult a professional regarding appropriate dosing.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 400mg is 1.1× the Tolerable Upper Intake Level (350mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a lower score because the amount of magnesium exceeds the recommended daily upper limit for safety.

Label

Product Label

Label for Magnesium Oxide 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Mineral
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

400 mg (95% DV)
Exceeds UL by 1.1× (UL: 350 mg) 316 studies (A:8, B:159)

Other Ingredients

Microcrystalline Cellulose Gelatin Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Once daily

Directions: Take one (1) capsule daily, preferably with a meal.

Warnings & Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper Evident Do not use if outer seal is broken or missing.

Formulation Notes

Gluten free Dairy free Soy free Nut free

Does not contain: Gluten, Sugar, Salt, Preservatives, Artificial Colors or Flavors.

Additional Information

Mineral

Energy production Muscle relaxation

Store in a cool, dry place.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Learn more at vsquality.net

Item No. VS-2281 1555127 GS 37

Metadata

Product Details

UPC / SKU7 66536 02281 6
DSLD Entry Date2019-01-07
Product TypeMineral
FormCapsule
BrandThe Vitamin Shoppe
DSLD ID184375
Data Updated2026-04-11
Research

Research Evidence

7
Research Sources
45
Avg Quality
6
Rct
1
Meta Analysis
C Effectiveness and safety of polyethylene-glycol-4000 versus sodium picosulphate plus magnesium oxide and citric acid for bowel cleansing before colonoscopy in children: A systematic review with meta-analysis
Meta Analysis Journal of pediatric gastroenterology and nutrition 2025 PubMed DOI
C A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls
Rct The Journal of clinical endocrinology and metabolism 2006 PubMed
C Senna Versus Magnesium Oxide for the Treatment of Chronic Constipation: A Randomized, Placebo-Controlled Trial
Rct The American journal of gastroenterology 2021 PubMed DOI
C The efficacy of magnesium oxide and sodium valproate in prevention of migraine headache: a randomized, controlled, double-blind, crossover study.
Rct Acta neurologica Belgica PubMed DOI
C A randomized, double-blind, placebo-controlled, multicenter study assessing the efficacy of magnesium oxide monohydrate in the treatment of nocturnal leg cramps.
Rct Nutrition journal PubMed DOI
C Comparative study between manitol and sodium picosulfate with magnesium oxide solutions in the preparation for colonoscopy.
Rct Revista do Colegio Brasileiro de Cirurgioes PubMed DOI
C Effect of magnesium oxide or citrate supplements on metabolic risk factors in kidney stone formers with idiopathic hyperoxaluria: a randomized clinical trial.
Rct Magnesium research PubMed DOI
View all evidence for Magnesium Oxide →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.