DHEA Spray Natural Wild Berry by Nature's Plus — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
33% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Spray(s) Serving Size

80 Servings

Other Combinations Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin E

1 IU (3% DV)

📊 Market median: 80.0mg (1390 products) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 0.67mg UL 1000mg

Dehydroepiandrosterone

12.5 mg

📊 Market median: 50.0mg (57 products) 📚 17 studies — no high-quality reviews

This product: 12.5mg UL 50mg

Hormone Support Complex

2.5 mg

Other Ingredients

purified Water Soy Lecithin Vegetable Glycerin Natural flavors Polysorbate 80 Citric Acid Medium Chain Triglycerides Stevia Potassium Sorbate

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (72% of products) Nutrient (2% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Shake well before using. As a dietary supplement, one spray daily. Spray under tongue, hold for 20 seconds and then swallow. Do not exceed recommended dosage unless supervised by a physician or health care professional.

⚠️ Warnings & Precautions

Do not exceed recommended dosage unless supervised by a physician or health care professional.

Notice: For adult use only.

DHEA should not be used except with a physician’s advice in the following conditions: pregnancy, lactation, any serious illness or during use of any prescription medication.

Keep out of reach of children.

🧪 Formulation Notes

Each nonaerosol spray supplies an activated complex of 100% pharmaceutical grade DHEA, highly active coenzymes and a proprietary base of essential metabolic factors.

Gluten Free

Additional Information

Nutritional Support for General Well-Being.

Div. of Natural Organics, Inc.

Product No. 49692 LBL. 1132978

Activated Micro-Soluble

w/Bioavailability Enhancing Cofactors

Gluten Free

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 49692 7

DSLD Entry Date 2019-01-07

Product Type Other Combinations

Form Liquid

Brand Nature's Plus

DSLD ID 184169

Data Updated 2026-04-11

Research Evidence

30 Research Sources

49 Avg Quality Score

21 Rct

5 Meta Analysis

2 Systematic Review

1 Other

1 Guideline

A Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI Cochrane

B Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B The auxiliary effect of oral nutritional supplements on fertility in women with diminished ovarian reserve: a systematic review and meta-analysis

Meta Analysis Annals of medicine 2025

PubMed DOI

B Impact of dehydroepiandrosterone (DHEA) supplementation on testosterone concentrations and BMI in elderly women: A meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2021

PubMed DOI

B Supplementation of dehydroepiandrosterone (DHEA) in pre- and postmenopausal women - position statement of expert panel of Polish Menopause and Andropause Society.

Guideline Ginekologia polska 2020

PubMed DOI

B Effect of Dehydroepiandrosterone and Testosterone Supplementation on Systemic Lipolysis

Rct The Journal of clinical endocrinology and metabolism 2016

PubMed DOI

C Impact of growth hormone and dehydroepiandrosterone on protein metabolism in glucocorticoid-treated patients

Rct The Journal of clinical endocrinology and metabolism 2008

PubMed DOI

C Associations between blood sex steroid concentrations and risk of major adverse cardiovascular events in healthy older women in Australia: a prospective cohort substudy of the ASPREE trial.

Rct The lancet. Healthy longevity

PubMed DOI

C Peculiar observations in measuring testosterone in women treated with oral contraceptives supplemented with dehydroepiandrosterone (DHEA)

Rct Clinica chimica acta; international journal of clinical chemistry 2014

PubMed DOI

C Dehydroepiandrosterone improves psychological well-being in male and female hypopituitary patients on maintenance growth hormone replacement

Rct The Journal of clinical endocrinology and metabolism 2006

PubMed

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