Home/ Supplements/ L Arginine/ L-Arginine 500 mg

L-Arginine 500 mg

product on market Capsule The Vitamin Shoppe Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

L-arginine is an amino acid used to support nitric oxide production and blood flow, while vitamin B6 contributes to metabolic functions. Research evidence for these specific benefits is generally moderate to limited. The product maintains a high safety profile for most healthy adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for L-Arginine 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

10 mg (590% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
500 mg
Market median: 500.0mg (143 products)

Other Ingredients

Gelatin Stearic Acid Magnesium Stearate Microcrystalline Cellulose Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one (1) capsule daily, preferably in between meals.

Warnings & Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Formulation Notes

Gluten free Dairy free Soy free Nut free Does not contain: Gluten, Sugar, Salt, Artificial Colors or Flavors.

Additional Information

Specialty Cardiovascular Exercise performance Nitric oxide

Store in a cool, dry place.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Item No. VS-1381 1046557 GS 37

Metadata

Product Details

UPC / SKU7 66536 01381 4
DSLD Entry Date2018-11-21
Product TypeOther Combinations
FormCapsule
BrandThe Vitamin Shoppe
DSLD ID183407
Data Updated2026-04-11
Research

Research Evidence

45
Research Sources
52
Avg Quality
12
Rct
11
Systematic Review
11
Meta Analysis
11
Clinical Trial
A Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Nutritional interventions for treating foot ulcers in people with diabetes
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2007 PubMed
B The Effect of Amino Acids on Wound Healing: A Systematic Review and Meta-Analysis on Arginine and Glutamine
Meta Analysis Nutrients 2021 PubMed DOI
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute ischaemic stroke
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use
Meta Analysis Nutrients 2023 PubMed DOI
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
B An Analysis of Popular Online Erectile Dysfunction Supplements
Systematic Review The journal of sexual medicine 2019 PubMed DOI
View all evidence for L Arginine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.