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Glucosamine/MSM

product on market Capsule Pure Encapsulations Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine sulfate and MSM provide moderate evidence for supporting joint health and cartilage maintenance. Turmeric and ginger extracts are researched for their anti-inflammatory properties, though evidence for their efficacy in joint support is often limited. This combination of ingredients is associated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine/MSM
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
MSM
500 mg
Market median: 1000.0mg (2 products)
Market median: 250.0mg (337 products) 127 studies (A:1, B:41)
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)

Other Ingredients

Vegetarian Capsule Ascorbyl Palmitate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: As a dietary supplement, take 2 capsules, 1-3 times daily, with meals.

Warnings & Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Do not take if you are sensitive to shellfish.

Keep out of the reach of children.

Use only if safety seal is intact.

Contains shellfish (crab, shrimp)

Formulation Notes

Certified by Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

OptiMSM

Gluten-free & Non-GMO

Contains shellfish (crab, shrimp)

Additional Information

Store in a cool, dry place.

Individual results may wary.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Scan to learn about our hypoallergenic supplements

Glucosamine/MSM with joint comfort herbs

Supports connective tissue health and joint comfort

GF

v7 code: GM6

Metadata

Product Details

UPC / SKU7 66298 00333 7
DSLD Entry Date2018-10-25
Product TypeOther Combinations
FormCapsule
BrandPure Encapsulations
DSLD ID182940
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.