Iso Tone by Advanced Nutrition Systems — Ingredients, Evidence & Safety

Product Label

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Label Data

2 Softgel(s) Serving Size

45 Servings

Other Combinations Product Type

25% Evidence Coverage

Supplement Facts — Evidence Check

Calories

10 Calorie(s)

Total Fat

1 Gram(s) (2% DV)

Vitamin E

13 IU (45% DV)

✅ Within RDA (0.6× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 8.71mg UL 1000mg

Iso Tone Body Toning Matrix

1600 mg

Other Ingredients

Gelatin Glycerin purified Water

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (98% of products) Structure/Function (81% of products) Nutrient (56% of products) Qualified Health (2% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take one serving (two softgels), up to three times daily with meals. Please read the entire label before use.

⚠️ Warnings & Precautions

Contains: Fish (Anchovy, Sardine, and Mackerel) and Soy

This product was produced in a facility that may also process ingredients containing milk, eggs, crustacean shellfish, tree nuts, peanuts, and wheat

Warning: Do not use if pregnant, nursing, or plan on becoming pregnant.

This product is intended for use by healthy adults over the age of 18.

Consult a physician or licensed qualified health care professional before using this product if you have, or have a family history of, any medical condition, or if you are using any other dietary supplement, prescription drug including, but not limited to, anti-coagulant, anti-diabetic and/or anti-hypertensive agents, or over-the-counter drug.

Do not use if safety seal under cap is broken or missing.

Keep out of reach of children.

🧪 Formulation Notes

Contains: Fish (Anchovy, Sardine, and Mackerel) and Soy

Human studies have demonstrated CLA may help reduce fat mass with a dose as low as 1.4g-3.4g per day. This product is to be used in conjunction with a healthy, reduced calorie diet and exercise plan. The amount of fat loss and change in body composition varies by individual and is related to your diet, exercise, age and body frame.

Powerful Thermogenic Rush + Stim-Free Fat Loss Support

Thermogenic + Stim-Free Fat Loss Support

Additional Information

Body Toner

Store in a cool, dry place.

Please recycle.

Made in the USA

Proudly made in the USA with carefully selected ingredients of international and domestic origin.

Formulated to drive weight and fat loss while toning and tightening the midsection, ANS' superior thermo-fat loss stack features its exclusively formulated Methyl Drive 3.0 and Iso Tone.

Combined together, this stack enables the body to reach its thermogenic and toning optimum and achieve intense weight loss results.

Energy Metabolize Tone Fat Loss

Product Details

DSLD Entry Date 2018-08-31

Product Type Other Combinations

Form Softgel Capsule

Brand Advanced Nutrition Systems

Bundle Dual Action Metabolic Enhancer

DSLD ID 180568

Data Updated 2026-04-11

Research Evidence

253 Research Sources

55 Avg Quality Score

128 Meta Analysis

52 Systematic Review

41 Rct

24 Clinical Trial

3 Regulatory Source

1 Narrative Review

1 Other

1 Guideline

1 Openfda Safety

A Vitamin E supplementation in pregnancy

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Systematic Review The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin E for Alzheimer's disease and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2008

PubMed DOI Cochrane

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

A Exercise for intermittent claudication

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis

Meta Analysis Nutritional neuroscience 2021

PubMed DOI

A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis

Meta Analysis European journal of clinical nutrition 2023

PubMed DOI

A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

Rct JAMA 2011

PubMed DOI

A Vitamin E for Alzheimer's dementia and mild cognitive impairment

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.

Guideline JAMA 2022

PubMed DOI

View all evidence for Vitamin E →