Home/ Supplements/ Coq10/ CoQ10 400 mg

CoQ10 400 mg

product on market Softgel Capsule Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Coenzyme Q-10 is a nutrient that supports cellular energy production and antioxidant activity. Research provides moderate evidence for its role in cardiovascular health and mitochondrial function. Other listed components are standard nutritional markers with no therapeutic effect.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for CoQ10 400 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Fat
0.5 Gram(s) (1% DV)
400 mg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)

Other Ingredients

Soybean Oil Gelatin Glycerin Water Soy Lecithin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take one softgel daily with a meal. For easier swallowing, take with water before and during ingestion.

Warnings & Precautions

Statin users see back panel

Statin users: Certain statin drugs can reduce CoQ10 levels in the body. Nature Made CoQ10 can help replenish this important nutrient.

Caution: If you are pregnant or nursing, and/or taking any medications, including blood thinners, please consult your physician before using this product.

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Contains: Soy.

Formulation Notes

No color added No artificial flavors No preservatives No starch Gluten free

Contains: Soy.

Additional Information

Everyday value #1 pharmacist recommended

List No. 4092 L201 Cat. A639 5A007

Naturally orange Helps support heart function and cellular energy production

USP Dietary Supplement Verified

CoQ10 is naturally orange in color. Found in most cells in the body, CoQ10 helps support heart function and cellular energy production.

Separation and settling is normal in this product.

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org Based on Pharmacy Times Survey of pharmacists recommending Coenzyme Q10 Supplements.

Metadata

Product Details

UPC / SKU0 31604 04092 5
DSLD Entry Date2018-08-31
Product TypeNon-Nutrient/Non-Botanical
FormSoftgel Capsule
BrandNature Made
DSLD ID180235
Data Updated2026-04-11
Research

Research Evidence

202
Research Sources
55
Avg Quality
86
Meta Analysis
62
Systematic Review
28
Rct
17
Clinical Trial
4
Regulatory Source
2
Other
1
Narrative Review
1
Openfda Safety
A Coenzyme Q10 for heart failure
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
A Cardioprotective interventions for cancer patients receiving anthracyclines
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis
Meta Analysis BMJ open 2021 PubMed DOI
A Effects of coenzyme Q10 supplementation on statin-induced myopathy: a meta-analysis of randomized controlled trials
Meta Analysis Irish journal of medical science 2022 PubMed DOI
B Cardioprotective interventions for cancer patients receiving anthracyclines
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
B Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
B Efficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis
Meta Analysis Reproductive sciences (Thousand Oaks, Calif.) 2023 PubMed DOI
B Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials
Meta Analysis International journal of molecular sciences 2020 PubMed DOI
B Effects of coenzyme Q10 supplementation on myopathy in statin-treated patients: a systematic review and meta-analysis
Meta Analysis Journal of nutritional science 2025 PubMed DOI
B Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Coq10 →
Compare

Similar Products

CoQ10 200 mg
VitaCeutical Labs · Softgel Capsule
100
CoQ10 100 mg
VitaCeutical Labs · Softgel Capsule
100
ClearQ Clear Base E 400 IU With CoQ10 50 mg
Natural Factors · Softgel Capsule
100
ClearQ Clear Base E 400 IU With CoQ10 50 mg
Natural Factors · Softgel Capsule
100
Ubiquinol 50 mg
Bronson · Softgel Capsule
100
View all Coq10 products →
Coq10 research Best Coq10 All Coq10 products More from Nature Made View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.