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Maximum Strength D3 10,000 IU

product on market Softgel Capsule Nature Made Safety: 60/100
60/100

Review before taking

  • Vitamin D3: 0.25mg is 2.5× the Tolerable Upper Intake Level (0.1mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin D3 is supported by strong evidence for maintaining bone health and supporting immune function. However, the high dosage of 10,000 IU may pose safety concerns regarding toxicity or hypercalcemia in some individuals. This supplement provides a potent dose that requires careful monitoring.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin D3: 0.25mg is 2.5× the Tolerable Upper Intake Level (0.1mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 2.5 times the recommended maximum daily limit for Vitamin D3.

Label

Product Label

Label for Maximum Strength D3 10,000 IU
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mcg (2500% DV)
Exceeds UL by 2.5× (UL: 0.1 mg) 608 studies (A:16, B:251)

Other Ingredients

Soybean Oil Gelatin Glycerin Corn Oil Water Color added
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Consult your healthcare professional before use. Take one softgel daily with a meal. For easier swallowing, take with water before and during ingestion.

Warnings & Precautions

Caution: Do not exceed one softgel daily. Do not take longer than recommended by your healthcare professional.

Do not take if you are pregnant or nursing; have kidney disease; known hypersensitivity to vitamin D; hypercalcemia (high blood calcium) or may have sensitivity to hypercalcemia, or conditions such as cancer, hyperparathyroidism, sarcoidosis or other granulomatous disorders; or are on medications, unless directed by your healthcare professional.

When taking this product, it is recommended to have your vitamin D and calcium blood levels monitored by your healthcare professional.

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Formulation Notes

Maximum Strength D3 10,000 IU

Nature Made Maximum Strength D provides 10,000 IU of vitamin D3.

Color derived from natural source - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free

Additional Information

List No: 2888 L202 Cat. A679 5A004

#1 pharmacist recommended

Maximum strength for individuals diagnosed with vitamin D deficiency

Supports bone, teeth, muscle and immune health Helps improve calcium absorption Maximum 10,000 IU - For short-term use by adults diagnosed as vitamin D deficient to help restore healthy vitamin D levels. For more information, visit NatureMade.com.

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Vitamin D3 softgels are made to Nature Made’s guaranteed purity and potency standards. As diagnosed by a healthcare professional using appropriate biomarkers. Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin supplements.

Metadata

Product Details

UPC / SKU0 31604 02888 6
DSLD Entry Date2018-08-31
Product TypeVitamin
FormSoftgel Capsule
DSLD ID179943
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.