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Maximum Strength Magnesium 500 mg

product on market Softgel Capsule Nature Made Safety: 87/100
87/100

This product is generally safe

  • Magnesium: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)
  • 33% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Magnesium is supported by strong evidence for its role in muscle function and nervous system health. While the ingredient profile is focused, the overall evidence coverage for this specific formulation is limited. The product maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Maximum Strength Magnesium 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Mineral
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Fat
0.5 Gram(s) (1% DV)
500 mg (125% DV)
Exceeds UL by 1.4× (UL: 350 mg) 316 studies (A:8, B:159)

Other Ingredients

Medium Chain Triglycerides Gelatin Glycerin Soy Lecithin Water Colors added
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Consult your health care professional before use. For easier swallowing, take with water before and during ingestion. Take one softgel daily, with a meal.

Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing. Caution: Do not exceed one softgel daily or take with other products that contain magnesium, unless recommended by your health care professional. Product may cause gastrointestinal disturbance including diarrhea.

Consult a physician before use, if you have kidney disease or if you are taking prescription medications.

Contains: Soy.

Formulation Notes

Nature Made Maximum Strength Magnesium provides 500 mg of magnesium, a mineral essential in supporting optimal health: Helps support nerve, heart, and muscle function Helps support healthy bones and teeth, and is essential in converting food into cellular energy

Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free

Contains: Soy.

Additional Information

List No. 2887 L201 Cat. A697 5A007

Maximum strength for individuals diagnosed with low levels of magnesium

Strength levels of Magnesium R Regular 250 mg or below E Extra about 250 mg up to 400 mg M Maximum above 400 mg up to 500 mg M Maximum 500 mg - Helps restore healthy levels of magnesium in adults with low levels. For more information, visit NatureMade.com.

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Encapsulated and quality tested in the U.S.A. Magnesium softgels are made to Nature Made’s guaranteed purity and potency standards.

Metadata

Product Details

DSLD Entry Date2018-09-21
Product TypeMineral
FormSoftgel Capsule
DSLD ID179940
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
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Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.