Sleep

product on market Softgel Capsule Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Melatonin and L-theanine are supported by moderate to strong evidence for promoting sleep onset and relaxation. Melatonin helps regulate the sleep-wake cycle, while L-theanine may reduce anxiety to improve sleep quality. These ingredients are generally well-tolerated and recognized for their efficacy in sleep support.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Sleep
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Softgel(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
200 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
3 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)

Other Ingredients

Medium Chain Triglycerides Gelatin Glycerin Soy Lecithin Water yellow Beeswax Colors added
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take one Nature Made Sleep softgel one hour before bedtime. Do not exceed one softgel daily unless recommended by a health care professional. For easier swallowing, take with water before and during ingestion.

Warnings & Precautions

Do not exceed one softgel daily unless recommended by a health care professional.

Keep out of the reach of children.

Do not use if tamper evident printed foil seal over softgels is broken.

Warnings: This product contains melatonin.

Do not use this product unless advised by a physician if you are pregnant, attempting to become pregnant, or nursing; or if you are taking any medications or have any chronic disease, including hypertension (high blood pressure), diabetes, or an endocrine, auto-immune, depressive, bleeding or seizure disorder.

Do not drive a motor vehicle or operate machinery when taking melatonin.

Not intended for individuals under the age of 18 years.

Consult a health care professional if you are experiencing persistent sleep difficulties.

Contains: Soy.

Formulation Notes

100% drug free

Nature Made Sleep contains two ingredients to help support sleep - L-theanine and melatonin.

Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free

Warnings: This product contains melatonin.

Contains: Soy.

Additional Information

Your best sleep naturally Natural acting sleep aid

Fall asleep naturally Ingredients to help relax the mind and support sleep Actual size Night supply

Enjoy a good night's sleep naturally.

L-theanine is an amino acid, which originally discovered as a constituent of green tea in 1949, and is now used in its synthetic and natural form globally. Clinical studies show L-theanine helps relax the mind. Melatonin plays a natural role in the body's sleep cycle. Both ingredients can help you fall asleep naturally.

Store in a cool, dry place.

List No. 2575 P202 Cat. A880 1B220

Metadata

Product Details

UPC / SKU0 31604 02575 5
DSLD Entry Date2018-08-31
Product TypeNon-Nutrient/Non-Botanical
FormSoftgel Capsule
DSLD ID179653
Data Updated2026-04-11
Research

Research Evidence

37
Research Sources
53
Avg Quality
22
Rct
10
Systematic Review
3
Meta Analysis
1
Clinical Trial
1
Openfda Safety
B Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials
Systematic Review Nutritional neuroscience 2026 PubMed DOI
B The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis
Meta Analysis Sleep medicine reviews 2025 PubMed DOI
B The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness
Rct Nutritional neuroscience 2010 PubMed DOI
B Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial
Rct Nutrients 2019 PubMed DOI
B The Role of Supplements and Over-the-Counter Products to Improve Sleep in Children: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrition reviews 2025 PubMed DOI
B Effect of Alpha-S1-Casein Tryptic Hydrolysate and L-Theanine on Poor Sleep Quality: A Double Blind, Randomized Placebo-Controlled Crossover Trial
Rct Nutrients 2022 PubMed DOI
B Effect of L-theanine on selective attention in a traffic-related reaction task in sleep-deprived young adults: a double-blind placebo-controlled, crossover study
Rct Nutritional neuroscience 2025 PubMed DOI
B The combined effects of L-theanine and caffeine on cognitive performance and mood
Rct Nutritional neuroscience 2008 PubMed DOI
B Acute effects of tea constituents L-theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2014 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.