High Potency Biotin 2500 mcg by Nature Made — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Softgel(s) Serving Size

Vitamin Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Biotin

2500 mcg (833% DV)

📊 83.3× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 2.5mg

Other Ingredients

Soybean Oil Gelatin Glycerin yellow Beeswax Water Soy Lecithin Colors added

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (91% of products) Nutrient (57% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Take one softgel daily with a meal. For easier swallowing, take with water before and during ingestion.

⚠️ Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Contains: Soy.

🧪 Formulation Notes

Colors derived from natural sources - No synthetic dyes No artificial flavors No preservatives No yeast or starch Gluten free

Contains: Soy.

Additional Information

#1 pharmacist recommended High potency

USP Dietary Supplement Verified

May help support healthy hair, skin & nails

Biotin may help support healthy hair, skin and nails in those that are biotin deficient. Biotin also supports carbohydrate, protein & fat metabolism.

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org Based on Pharmacy Times Survey of pharmacists recommending Letter Vitamin Supplements.

List No. 2546Z L201 Cat. A521 5A002

Product Details

UPC / SKU 0 31604 42546 3

DSLD Entry Date 2018-08-31

Product Type Vitamin

Form Softgel Capsule

Brand Nature Made

DSLD ID 179651

Data Updated 2026-04-11

Research Evidence

31 Research Sources

53 Avg Quality Score

12 Meta Analysis

9 Systematic Review

5 Rct

2 Clinical Trial

1 Regulatory Source

1 Openfda Safety

B Pentasaccharides for the treatment of deep vein thrombosis

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

B Quantitative comparison of the efficacy of clinical drug treatments for primary progressive multiple sclerosis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2023

PubMed DOI

B Dietary interventions for multiple sclerosis-related outcomes

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

B Interventions for infantile seborrhoeic dermatitis (including cradle cap)

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

B Effect of varicocelectomy on sperm deoxyribonucleic acid fragmentation rates in infertile men with clinical varicocele: a systematic review and meta-analysis

Meta Analysis Fertility and sterility 2021

PubMed DOI

B Effect of feeding biotin on milk production and hoof health in lactating dairy cows: a quantitative assessment

Meta Analysis Journal of dairy science 2011

PubMed DOI

B Factitious Graves' Disease Due to Biotin Immunoassay Interference-A Case and Review of the Literature

Systematic Review The Journal of clinical endocrinology and metabolism 2016

PubMed DOI

B Effect of biotin on milk performance of dairy cattle: a meta-analysis

Meta Analysis Journal of dairy science 2011

PubMed DOI

B PROVIT: Supplementary Probiotic Treatment and Vitamin B7 in Depression-A Randomized Controlled Trial