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SAM-e Complete 400 mg

product on market Tablet or Pill Nature Made Safety: 100/100
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This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade
Label

Product Label

Label for SAM-e Complete 400 mg
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Details

Label Data

1 Tablet(s)
Serving Size
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Protein
1 Gram(s)
400 mg
Market median: 200.0mg (52 products) 12 studies (A:0, B:6)

Other Ingredients

S-Adenosylmethionine Tosylate Disulfate Cellulose Gel Methacrylic Acid Copolymer Stearic Acid Silicon Dioxide Triethyl Citrate Magnesium Stearate Color added Mannitol Sodium Starch Glycolate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Start with 1 tablet per day. For easier swallowing, take with water before and during ingestion. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of tablet (maximum 1600 mg/day) until benefits are achieved.

Warnings & Precautions

Foil blister pack ensures safety and freshness. Do not use if tamper evident printed foil seal over tablets is broken.

Store in a cool, dry place, out of reach of children.

Caution: People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision.

If you are pregnant or nursing, or taking prescription medications, including antidepressants, consult your doctor before using this product.

Formulation Notes

This product is gluten free.

Additional Information

When your emotions are healthy & balanced, you feel like yourself. However, sometimes emotions can get out of balance, causing you to feel moody. This imbalance can be associated with low levels of SAM-e (S-adenosylmethionine), a naturally occurring molecule produced by the body. SAM-e levels can run low due to various factors such as diet and aging. Mood improvement Days Replenish your SAM-e levels and feel the difference in as little as 7-14 days when taken daily. Helps support joint comfort Nature Made SAM-e also helps support joint comfort, which may naturally deteriorate with physical activity and age. SAM-e provides a source of sulfur, which is a critical component of joint tissue. 100% money back 100% money back guarantee Visit NatureMade.com/guarantee for details. Nature Made St. John's Wart is the #1 pharmacist recommended mood health supplement followed by Nature Made SAM-E based on the U.S. News & World Report - Pharmacy Time Survery

SAM-e is a moisture sensitive product. That is why at Nature Made, we use foil blister packaging to ensure that each tablet of our SAM-e Complete is fresh and safe when you take it.

Store in a cool, dry place, out of reach of children.

Restores a healthy mood in as little as 7-14 days when taken daily Complete studies have shown that SAM-e helps support a healthy mood & joint comfort

Money back guarantee Helps support a healthy mood & joint comfort Clinically studied ingredient

List No: 1107ZS P200 Cat: A852 1A147

Metadata

Product Details

UPC / SKU0 31604 41107 7
DSLD Entry Date2018-07-25
Product TypeOther Combinations
FormTablet or Pill
DSLD ID179341
Data Updated2026-04-11
Research

Research Evidence

We're building the evidence profile for this product's ingredients. Check back soon.

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.