🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Protein
1 Gram(s)
400 mg
📊 Market median: 200.0mg (52 products) 📚 10 studies (Tier A: 0, B: 6)
This product: 400mg

Other Ingredients

S-Adenosylmethionine Tosylate Disulfate Cellulose Gel Methacrylic Acid Copolymer Stearic Acid Silicon Dioxide Triethyl Citrate Magnesium Stearate Color added Mannitol Sodium Starch Glycolate

Label Claims — Verification

All Other
Structure/Function

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Start with 1 tablet per day. For easier swallowing, take with water before and during ingestion. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of tablet (maximum 1600 mg/day) until benefits are achieved.

⚠️ Warnings & Precautions

Foil blister pack ensures safety and freshness. Do not use if tamper evident printed foil seal over tablets is broken.

Store in a cool, dry place, out of reach of children.

Caution: People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision.

If you are pregnant or nursing, or taking prescription medications, including antidepressants, consult your doctor before using this product.

🧪 Formulation Notes

This product is gluten free.

Additional Information

When your emotions are healthy & balanced, you feel like yourself. However, sometimes emotions can get out of balance, causing you to feel moody. This imbalance can be associated with low levels of SAM-e (S-adenosylmethionine), a naturally occurring molecule produced by the body. SAM-e levels can run low due to various factors such as diet and aging. Mood improvement Days Replenish your SAM-e levels and feel the difference in as little as 7-14 days when taken daily. Helps support joint comfort Nature Made SAM-e also helps support joint comfort, which may naturally deteriorate with physical activity and age. SAM-e provides a source of sulfur, which is a critical component of joint tissue. 100% money back 100% money back guarantee Visit NatureMade.com/guarantee for details. Nature Made St. John's Wart is the #1 pharmacist recommended mood health supplement followed by Nature Made SAM-E based on the U.S. News & World Report - Pharmacy Time Survery

SAM-e is a moisture sensitive product. That is why at Nature Made, we use foil blister packaging to ensure that each tablet of our SAM-e Complete is fresh and safe when you take it.

Store in a cool, dry place, out of reach of children.

Restores a healthy mood in as little as 7-14 days when taken daily Complete studies have shown that SAM-e helps support a healthy mood & joint comfort

Money back guarantee Helps support a healthy mood & joint comfort Clinically studied ingredient

List No: 1100S P200 Cat: A852 1A146

Product Details

UPC / SKU 0 31604 01100 0
DSLD Entry Date 2018-07-25
Product Type Other Combinations
Form Tablet or Pill
Brand Nature Made
DSLD ID 179339
Data Updated 2026-04-11

Research Evidence

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