🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Lozenge(s) Serving Size
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

800 mcg (200% DV)
✅ 2.0× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.8mg UL 1.0mg

Other Ingredients

Fructose Sorbitol Cellulose Gum natural Cherry flavor Vegetable Stearin Carmine Luo Han Guo Silica Mannitol Dextrose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, adults take one (1) lozenge daily, or as directed by a health care professional. Allow lozenge to dissolve in the mouth.

⚠️ Warnings & Precautions

Keep out of reach of children.

🧪 Formulation Notes

Contains no salt, dairy, yeast, wheat, gluten, soy, preservatives, artificial colors or flavors.

Additional Information

Store in a cool, dry place and away from direct light.

New day. Fresh start. Better health. Helps support nervous system and cardiovascular health

Methylfolate (5-MTHF) is the most biologically active form of folate in the human body. Unlike folic acid, it needs no enzymatic conversion within the body, and is therefore six times more bioavailable. Many people suffer from a genetic disorder that prevents them from adequately converting folate into 5-MTHF. Since it does not require conversion, supplemental 5-MTHF quickly increases both blood and cellular levels of this critical nutrient. In addition to its well-known role in supporting healthy fetal neural development, 5-MTHF is important in the synthesis of acetylcholine, an important neurotransmitter. 5-MTHF also supports a healthy cardiovascular system by helping to keep homocysteine levels within the normal range. Homocysteine is a known risk factor for cardiovascular disease.

Quality & potency guaranteed

3472 /T001

Product Details

UPC / SKU 7 87500 03472 7
DSLD Entry Date 2018-03-23
Product Type Vitamin
Form Lozenge
DSLD ID 174228
Data Updated 2026-04-11

Research Evidence

363 Research Sources
57 Avg Quality Score
187 Meta Analysis
56 Systematic Review
54 Rct
29 Guideline
26 Clinical Trial
6 Cochrane Review
2 Regulatory Source
1 Other
1 Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025
View all evidence for Folate →

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