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Calcium 500 +D

product on market Tablet or Pill 21st Century Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Calcium and vitamin D3 are supported by strong evidence for maintaining bone density and supporting skeletal health. Vitamin D3 facilitates the absorption of calcium in the gut to optimize bone mineralization. These ingredients are widely researched for their role in preventing bone loss.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calcium 500 +D
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
45
Servings
Single Vitamin and Mineral
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

800 IU (200% DV)
1.3× RDA — within safe limits 608 studies (A:16, B:251)
Calcium
1000 mg (100% DV)

Other Ingredients

Croscarmellose Sodium Cellulose Titanium Dioxide Magnesium Stearate Stearic Acid Artificial Colors
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Approved Health
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take up to (2) tablets daily with any meal for maximum daily results, or as directed by your healthcare provider. Do not exceed recommended dosage.

Warnings & Precautions

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

Formulation Notes

Oyster Shell

Extra Vitamin D

Contains a shellfish ingredient (oyster shell).

No added Sugar, Salt, Yeast, Preservatives or Artificial Flavors.

Additional Information

20% Free

MADE IN USA

D3

Calcium 500 +D Oyster Shell

Regular exercise and a healthy diet with enough calcium helps teen and young adult Caucasian and Asian women maintain good bone health and may reduce their high risk of osteoporosis later in life. Adequate calcium intake is important, but daily intakes above about 2,000 mg are not likely to provide any additional benefit. Now with extra Vitamin D. Vitamin D is essential for use of calcium and necessary for healthy bones, teeth and cartilage.*

1107 0407

Store at room temperature.

Unconditionally guaranteed for purity, freshness and label potency.

Metadata

Product Details

UPC / SKU7 40985 22336 9
DSLD Entry Date2012-08-24
Product TypeSingle Vitamin and Mineral
FormTablet or Pill
Brand21st Century
DSLD ID11105
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.