🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
45 Servings
Single Vitamin and Mineral Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

800 IU (200% DV)
✅ 1.3× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.02mg UL 0.1mg
Calcium
1000 mg (100% DV)

Other Ingredients

Croscarmellose Sodium Cellulose Titanium Dioxide Magnesium Stearate Stearic Acid Artificial Colors

Label Claims — Verification

Nutrient
All Other
Approved Health
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (54% of products) Approved Health (3% of products)

Target Groups

Adult Female (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Take up to (2) tablets daily with any meal for maximum daily results, or as directed by your healthcare provider. Do not exceed recommended dosage.

⚠️ Warnings & Precautions

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

Oyster Shell

Extra Vitamin D

Contains a shellfish ingredient (oyster shell).

No added Sugar, Salt, Yeast, Preservatives or Artificial Flavors.

Additional Information

20% Free

MADE IN USA

D3

Calcium 500 +D Oyster Shell

Regular exercise and a healthy diet with enough calcium helps teen and young adult Caucasian and Asian women maintain good bone health and may reduce their high risk of osteoporosis later in life. Adequate calcium intake is important, but daily intakes above about 2,000 mg are not likely to provide any additional benefit. Now with extra Vitamin D. Vitamin D is essential for use of calcium and necessary for healthy bones, teeth and cartilage.*

1107 0407

Store at room temperature.

Unconditionally guaranteed for purity, freshness and label potency.

Product Details

UPC / SKU 7 40985 22336 9
DSLD Entry Date 2012-08-24
Product Type Single Vitamin and Mineral
Form Tablet or Pill
Brand 21st Century
DSLD ID 11105
Data Updated 2026-04-11

Research Evidence

849 Research Sources
56 Avg Quality Score
450 Meta Analysis
152 Rct
137 Systematic Review
73 Clinical Trial
11 Regulatory Source
7 Other
7 Guideline
3 Openfda Safety
2 Cochrane Review
2 Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021
View all evidence for Electrolytes →

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