⚠️ Mechanism
Zinc chelates tetracycline antibiotics, reducing absorption of both.
📋 Effect
Reduced tetracycline and zinc absorption
💊 Management
Separate doses by at least 2 hours before or 4 hours after tetracycline.
Plain Language Summary
This combination can be problematic because zinc can interfere with how your body absorbs tetracycline antibiotics. The zinc binds to the medication, which may prevent the antibiotic from working as intended.
Source
Neuvonen PJ. Drugs 1976
Supporting Research
Oral zinc for treating diarrhoea in children
Zinc for the prevention or treatment of acute viral respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials
Compression bandages or stockings versus no compression for treating venous leg ulcers
Zinc for the common cold
Interventions for managing halitosis
Interventions for itch in people with advanced chronic kidney disease
Topical antimicrobial agents for treating foot ulcers in people with diabetes
Local interventions for the management of alveolar osteitis (dry socket)
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.