Zinc × Penicillamine
MODERATE
Well-Established Evidence
Mechanism
Zinc reduces penicillamine absorption and vice versa.
Effect
Reduced efficacy of both agents
Management
Separate doses by at least 2 hours.
Plain Language Summary
AI-generated · Qwen 3.6 · grounded in 2 sources · methodologyThis interaction is considered moderate and can affect how well your medication works. Zinc and penicillamine can prevent each other from being properly absorbed, which may reduce the effectiveness of both. Separating these doses by at least two hours can help avoid this interference.
Source
Harkness JA, Blake DR. BMJ 1982
Research
Supporting Research
Oral zinc for treating diarrhoea in children
Zinc for the prevention or treatment of acute viral respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials
Compression bandages or stockings versus no compression for treating venous leg ulcers
Zinc for the common cold
Interventions for managing halitosis
Interventions for itch in people with advanced chronic kidney disease
Topical antimicrobial agents for treating foot ulcers in people with diabetes
Local interventions for the management of alveolar osteitis (dry socket)
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.