Home/ Interactions/ Zinc × Fluoroquinolones

Zinc × Fluoroquinolones

MODERATE Well-Established Evidence

Mechanism

Zinc chelates fluoroquinolone antibiotics, reducing absorption.

Effect

Reduced antibiotic absorption and efficacy

Management

Separate doses by at least 2 hours before or 6 hours after antibiotic.

Plain Language Summary

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This combination can be problematic because zinc binds to the antibiotic, which may prevent your body from absorbing the full dose. This can make the treatment less effective. The data indicates that doses should be separated by at least 2 hours before or 6 hours after the antibiotic.

Source

FDA fluoroquinolone labeling

Research

Supporting Research

Oral zinc for treating diarrhoea in children
Zinc for the prevention or treatment of acute viral respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials
Compression bandages or stockings versus no compression for treating venous leg ulcers
Zinc for the common cold
Interventions for managing halitosis
Interventions for itch in people with advanced chronic kidney disease
Topical antimicrobial agents for treating foot ulcers in people with diabetes
Local interventions for the management of alveolar osteitis (dry socket)
← Zinc All Interactions →

Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.