Vitamin D × Verapamil
MINOR
Theoretical Evidence
Mechanism
Vitamin D promotes calcium absorption, which may counteract verapamil's calcium channel blocking effect.
Effect
Possible reduced verapamil efficacy at very high vitamin D doses
Management
Moderate vitamin D intake is safe. Avoid extreme doses without monitoring.
Plain Language Summary
AI-generated · Qwen 3.6 · grounded in 2 sources · methodologyThis interaction is considered minor and is generally safe with moderate Vitamin D intake. However, taking extremely high doses of Vitamin D could potentially reduce the effectiveness of Verapamil.
Source
Theoretical based on calcium-channel mechanism
Research
Supporting Research
Interventions for preventing falls in older people in care facilities and hospitals
High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Interventions for preventing falls in older people living in the community
Interventions for preventing falls in older people in nursing care facilities and hospitals
Interventions for preventing falls in older people living in the community
Interventions for preventing falls in older people in care facilities and hospitals
Interventions for preventing falls in older people in care facilities
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.