Home/ Interactions/ Probiotics × Immunosuppressants

Probiotics × Immunosuppressants

MODERATE Probable Evidence

Mechanism

Probiotics contain live organisms that may cause infection in immunocompromised patients.

Effect

Possible bacteremia or fungemia in immunosuppressed patients

Management

Avoid in transplant patients and those on high-dose immunosuppressants. Consult specialist.

Plain Language Summary

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This combination can be dangerous for individuals with a weakened immune system. Because probiotics contain live bacteria, they may cause an infection in the bloodstream.

Source

Borriello SP et al. Am J Clin Nutr 2003; Honeycutt T et al. Transplantation 2004

Research

Supporting Research

Probiotics for maintenance of remission in ulcerative colitis
Probiotics for induction of remission in ulcerative colitis
Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Effect of chicory-derived inulin-type fructans on abundance of Bifidobacterium and on bowel function: a systematic review with meta-analyses
Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis
Probiotics for preventing gestational diabetes
Probiotics for treating acute infectious diarrhoea
Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
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Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications.