⚠️ Mechanism
Probiotics contain live organisms that may cause infection in immunocompromised patients.
📋 Effect
Possible bacteremia or fungemia in immunosuppressed patients
💊 Management
Avoid in transplant patients and those on high-dose immunosuppressants. Consult specialist.
Plain Language Summary
This combination can be dangerous for individuals with a weakened immune system. Because probiotics contain live bacteria, they may cause an infection in the bloodstream.
Source
Borriello SP et al. Am J Clin Nutr 2003; Honeycutt T et al. Transplantation 2004
Supporting Research
Probiotics for maintenance of remission in ulcerative colitis
Probiotics for induction of remission in ulcerative colitis
Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Effect of chicory-derived inulin-type fructans on abundance of Bifidobacterium and on bowel function: a systematic review with meta-analyses
Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis
Probiotics for preventing gestational diabetes
Probiotics for treating acute infectious diarrhoea
Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.