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Omega 3 × Antiplatelet Drugs

MINOR INTERACTION — Possible Evidence

⚠️ Mechanism

Omega-3 fatty acids at high doses may slightly increase bleeding time.

📋 Effect

Minimal increased bleeding risk at doses <3g/day

💊 Management

Doses <3g/day generally safe. Monitor for bleeding if higher doses used.

Plain Language Summary

This combination is generally safe at doses below 3 grams per day. However, taking very high doses of Omega-3 may slightly increase the time it takes for your blood to clot, which could lead to a small increase in bleeding risk.

Source

Kris-Etherton PM et al. Circulation 2002 AHA advisory

Supporting Research

Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease PMID:30521670 DOI:10.1002/14651858.CD003177.pub4 2018
Non-immunosuppressive treatment for IgA nephropathy PMID:38299639 DOI:10.1002/14651858.CD003962.pub3 2024
Interventions for fatigue and weight loss in adults with advanced progressive illness PMID:22258985 DOI:10.1002/14651858.CD008427.pub2 2012
Motor control exercise for chronic non-specific low-back pain PMID:26742533 DOI:10.1002/14651858.CD012004 2016
Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease PMID:30019767 DOI:10.1002/14651858.CD012345.pub2 2018
Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease PMID:30484282 DOI:10.1002/14651858.CD012345.pub3 2018
Reduced or modified dietary fat for preventing cardiovascular disease PMID:22592684 DOI:10.1002/14651858.CD002137.pub3 2012
WITHDRAWN: Interventions for fatigue and weight loss in adults with advanced progressive illness PMID:28387447 DOI:10.1002/14651858.CD008427.pub3 2017
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.