⚠️ Mechanism
Niacin can increase insulin resistance and raise blood glucose levels, counteracting diabetes medications.
📋 Effect
Worsening glycemic control; increased insulin requirements
💊 Management
Monitor blood glucose closely. Use low-dose niacin (<2g/day) if needed.
Plain Language Summary
This combination requires caution because niacin can raise your blood sugar levels. This may make your diabetes medications less effective at controlling your glucose.
Source
Vega GL et al. Arch Intern Med 2003; AIM-HIGH Trial
Supporting Research
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Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
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Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials
Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.