⚠️ Mechanism
Niacin may have mild antiplatelet effects at high doses.
📋 Effect
Possible additive bleeding risk at very high doses
💊 Management
Monitor INR if on warfarin with high-dose niacin. Minor concern at typical doses.
Plain Language Summary
This combination is generally safe at typical doses, but it may pose a minor risk at very high doses. Taking large amounts of niacin can slightly increase the risk of bleeding when used with blood-thinning medications.
Source
Ghosh SK et al. J R Soc Med 1987
Supporting Research
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Medical Disclaimer: This interaction record is for informational and educational purposes only and does not constitute medical advice. Drug-supplement interactions can be dangerous. Always consult your healthcare provider or pharmacist before combining any supplement with prescription medications. Do not stop or change any medication without professional guidance.